DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p24-1 and Tmed6

DIOPT Version :9

Sequence 1:	NP_001259465.1	Gene:	p24-1 / 32140	FlyBaseID:	FBgn0030341	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_079734.1	Gene:	Tmed6 / 66269	MGIID:	1913519	Length:	239	Species:	Mus musculus

Alignment Length:	216	Identity:	58/216 - (26%)
Similarity:	90/216 - (41%)	Gaps:	55/216 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EFTFDLADNAVDCFYEEIKKNSSAYFEFQVS--AGGQLD--VDVTLKDPQGKVIYSLEKATFDSH 81
            :|...::..|::||::...:....||.::|.  .|...|  :..|...|||.:|        |:.
Mouse    43 DFAIVVSPGAIECFWQFADQMGYLYFSYEVQRILGMSHDRHIVATAHTPQGFLI--------DTS 99

  Fly    82 Q-------FVAETTGVYTACFGNQFSAFSHKIVYVDFQVGEEPALPGVDEHATVLTQMETSSQAI 139
            |       |..:.||.|..|..|:.:.||...||::|.|..|.  |.||.           .|:.
Mouse   100 QDVRGQINFATQETGFYQLCLKNEQNRFSSIQVYLNFGVFYEG--PEVDH-----------KQSQ 151

  Fly   140 HKGLNDILDA----------QTHHRLR---EAQGRKRAEDLNQR-----VMVWSSLETAAVIVIG 186
            .|.|||.|||          |..|..|   .|:.||.|:....:     |..||:.::.|:::.|
Mouse   152 RKQLNDTLDAIKDSTQRVENQVFHMWRFYNYARMRKVADFFLLQSNYTYVNWWSTAQSLAIVLSG 216

  Fly   187 LVQIMVLRNFFT-----DRKP 202
            .:|:..|:..||     .:||
Mouse   217 ALQLYFLKRLFTASTTDTKKP 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p24-1	NP_001259465.1	EMP24_GP25L	21..197	CDD:279450	54/204 (26%)
Tmed6	NP_079734.1	EMP24_GP25L	43..227	CDD:279450	54/204 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1693
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810