DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p24-1 and tmed5

DIOPT Version :9

Sequence 1:	NP_001259465.1	Gene:	p24-1 / 32140	FlyBaseID:	FBgn0030341	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	XP_031755940.1	Gene:	tmed5 / 549314	XenbaseID:	XB-GENE-951292	Length:	223	Species:	Xenopus tropicalis

Alignment Length:	232	Identity:	62/232 - (26%)
Similarity:	106/232 - (45%)	Gaps:	38/232 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNTQIVVFAVALMM------HCIS-----AVEFTFDLADNAVDCFYEEIKKNSSAYFEFQVSAGG 54
            |..:.|:|   ||:      ||:.     ..::||.|.....:||::.:|::::...|:||..|.
Frog     1 MGKEAVLF---LMLTHYTVRHCMGFSQSVDSDYTFTLPAGQKECFFQPMKRDATLEIEYQVLDGA 62

  Fly    55 QLDVDVTLKDPQGKVIYSLEKATFDSHQFVAETTGVYTACFGNQFSAFSHKIVYVDFQVGEEPAL 119
            .||||.:|..|.|:::.|.|:.:...|. |....|.|..||.|.||..|.|:::.      |..|
Frog    63 GLDVDFSLTSPNGELLLSEERQSDGVHS-VETIDGDYQFCFDNSFSRMSEKVIFF------ELIL 120

  Fly   120 PGVDEHATVLTQME---TSSQAIHKGLNDILDA--------------QTHHRLREAQGRKRAEDL 167
            ..:::....|...:   |.:..:...|.|||:.              ||..:..||:.|...|..
Frog   121 DHLNDEGNELEDWKSYITGTDLLDMKLEDILETINSVKGRLTKSAQIQTLLKAFEARDRNLQESN 185

  Fly   168 NQRVMVWSSLETAAVIVIGLVQIMVLRNFFTDRKPSQ 204
            .:||..||......::|:..:|:.:||:.|.|::.|:
Frog   186 FERVTFWSVFNLTVMVVVSALQVYMLRSLFEDKRKSR 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p24-1	NP_001259465.1	EMP24_GP25L	21..197	CDD:279450	52/192 (27%)
tmed5	XP_031755940.1	EMP24_GP25L	29..216	CDD:395878	52/193 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1292519at2759
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1790
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950