DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p24-1 and TMED6

DIOPT Version :9

Sequence 1:	NP_001259465.1	Gene:	p24-1 / 32140	FlyBaseID:	FBgn0030341	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_653277.2	Gene:	TMED6 / 146456	HGNCID:	28331	Length:	240	Species:	Homo sapiens

Alignment Length:	216	Identity:	57/216 - (26%)
Similarity:	85/216 - (39%)	Gaps:	57/216 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EFTFDLADNAVDCFYEEIKKNSSAYFEFQV--SAGGQLD--VDVTLKDPQGKVIYSLEKATFDSH 81
            :|...:.....:||::...:....||.::|  :.|...|  |..|..:|||.:|        |:.
Human    43 DFAIMIPPGGTECFWQFAHQTGYFYFSYEVQRTVGMSHDRHVAATAHNPQGFLI--------DTS 99

  Fly    82 Q-------FVAETTGVYTACFGNQFSAFSHKIVYVDFQVGEEPALPGVDEHATVLTQMETSSQAI 139
            |       |..:.||.|..|..||.:.|....||::|.|..|.  |..|.           .|..
Human   100 QGVRGQINFSTQETGFYQLCLSNQHNHFGSVQVYLNFGVFYEG--PETDH-----------KQKE 151

  Fly   140 HKGLNDILDA----------QTHHRLRE---AQGRKRAE------DLNQRVMVWSSLETAAVIVI 185
            .|.|||.|||          ...|..|.   |:.||.|:      :.|. |..||:.::..:|:.
Human   152 RKQLNDTLDAIEDGTQKVQNNIFHMWRYYNFARMRKMADFFLIQSNYNY-VNWWSTAQSLVIILS 215

  Fly   186 GLVQIMVLRNFF-----TDRK 201
            |::|:..|:..|     ||.|
Human   216 GILQLYFLKRLFNVPTTTDTK 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p24-1	NP_001259465.1	EMP24_GP25L	21..197	CDD:279450	53/205 (26%)
TMED6	NP_653277.2	EMP24_GP25L	43..228	CDD:279450	53/206 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1693
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810