DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp28c1 and CYP705A12

DIOPT Version :9

Sequence 1:	NP_001259464.1	Gene:	Cyp28c1 / 32138	FlyBaseID:	FBgn0030339	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_199072.1	Gene:	CYP705A12 / 834265	AraportID:	AT5G42580	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	540	Identity:	124/540 - (22%)
Similarity:	219/540 - (40%)	Gaps:	123/540 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLGAIYAFLVSNFGHWRRRGV---TEPRALPLFG--------SFPNMIWPRQHFTMDMRDIYMHY 65
            :|..:::||.......:.:|.   ..|.:||:.|        |.|:..:.:..|....   .:|.
plant    16 ILLCLFSFLCYALFFKKPKGFDLPPSPPSLPIIGHLHHLLSSSLPHKSFQKLSFKYGP---LLHL 77

  Fly    66 RNTHSYVGCYLLRAPKLLVLEPRLVYEIYVSAFSHFENNDAS---KMVDIAKDRLV-ALNPFVLE 126
            |         :...|.:||....:.||:       |..||.:   :.|.:.||.|| ..:.||..
plant    78 R---------IFNFPMVLVSSASMAYEV-------FRTNDVNVSYRFVPVNKDSLVFGSSGFVTA 126

  Fly   127 --GEEWRHQRAVFSTLLTNGRIRTTHAI----------MQRVCLDLCQFIAIKSAGGKDLDCIDL 179
              |:.|:..:.:.||     ::...||:          ::|.||||       ....:..:.:::
plant   127 PYGDYWKFMKKLIST-----KLLRPHALELSKGNRAEELRRFCLDL-------QGKARKKESVEI 179

  Fly   180 G---LRFTGESLFDCVLGIQARTFTDNPLPVVRQNHEMSAENRGLAIAGAVHGLFPNLPRWLRPK 241
            |   |:.|...:....:|   |:.::.. .|..:..|:  .|:..|:  :|...|.|:   .|..
plant   180 GKVALKLTNNIICRMSMG---RSCSEKN-GVAERAREL--VNKSFAL--SVKLFFSNM---FRKD 233

  Fly   242 VF--PRSHDRFYGQMISEALRLRRSKHQER------NDFINHLLEMQR----ELDLSEEDMASHA 294
            :.  .|..|.|..:::.|        |:|.      .|.|:||||..|    |..::.:.:.|..
plant   234 IMGVSREFDEFLERILVE--------HEENLEGDQDRDMIDHLLEAYRNEEAEYKITRKQIKSLI 290

  Fly   295 MTFMFDGLDTTSNSIAHCLLLLGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFNESL 359
            :.....|.|:::.:|...:..:..||....:|..|:..|..|..|.....|.:||||.|...|.|
plant   291 VEIFLGGTDSSAQTIQWTMAEILNNPGVLEKLRAEIDSVVGGKRLIQESDLPNLPYLQAVVKEGL 355

  Fly   360 RIYPAGGWASKTCTKEYELRGSHHSEPLKLRPGDHVMVPIYALHNDPDLYPEPDVFRPERFL--- 421
            |::|:.....:...:..|::..:..|...|      :|.:||::.|||.:.:||:|:|||||
plant   356 RLHPSAPVLLRVFGESCEVKEFYVPEKTTL------VVNLYAVNRDPDSWEDPDMFKPERFLVSS 414

  Fly   422 -DGGLKNCKQQGI-FLGFGNGPRQCVGMRLGLAMAKAALAAIVQRF------EVVVSPRTLNGTE 478
             .|..:..::|.: ::.||.|.|.|..::|.....:.|:.|:||.|      |.|.....::|..
plant   415 ISGDEEKIREQAVKYVTFGGGRRTCPAVKLAHIFMETAIGAMVQCFDWRIKGEKVYMEEAVSGLS 479

  Fly   479 L--------------DPLIF 484
            |              ||..|
plant   480 LKMAHPLKCTPVVRFDPFSF 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28c1	NP_001259464.1	p450	35..487	CDD:299894	120/514 (23%)
CYP705A12	NP_199072.1	CYP93	72..490	CDD:410748	110/473 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010