Protein Alignment Cyp28c1 and Cyp3a62

DIOPT Version :10

• Sequence 1: NP_572752.1
• Gene: Cyp28c1 / 32138
• FlyBaseID: FBgn0030339
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001019403.1
• Gene: Cyp3a62 / 170509
• RGDID: 1595919
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 484
• Identity: 132/484 - (27%)
• Similarity: 232/484 - (47%)
• Gaps: 62/484 - (12%)

  Fly     9 IATLLGAIYAFLVSNFGHWRRRGVTEPRALPLFGSFPNMIWPRQHFTMDMRDIYMHYRNTHSYVG 73
            :||:|..:|.:..|..|::::.|::.|:.||..|   |::..|..|....|..:..|.:..   |
  Rat    15 LATILVLLYLYGTSTHGNFKKLGISGPKPLPFVG---NILAYRHGFWEFDRHCHKKYGDIW---G 73

  Fly    74 CYLLRAPKLLVLEPRLVYEIYV-SAFSHFENNDASKMVDIAKDRLVALNPFVLEGEEWRHQRAVF 137
            .|..|.|.|.:.:|.::..:.| ..:|.|.|..:.....|.| :.:.|:    |.|||:..|.:.
  Rat    74 FYEGRQPILAITDPDIIKTVLVKECYSTFTNRRSFGPAGILK-KAITLS----EDEEWKRLRTLL 133

  Fly   138 STLLTNGRIRTTHAIMQRVCLDLCQFIAIKSAGGKDLDCIDLGLRFTGESLFDCVLGIQARTFTD 202
            |...|:|:::....|:.:....|.:.:..::..|..:...|:...::.:.:.....|:...:..:
  Rat   134 SPTFTSGKLKEMFPIINQYADLLVKNVKHEAEKGNPITMKDIFGAYSMDVITGTSFGVNVDSLNN 198

  Fly   203 NPLPVVRQNHEMSAEN----RGLAIAGAVHGLFPNLPRWLRP-------KVFPRSHDRFYGQMIS 256
            ...|.|::..::...|    ..|::.     |||    :|.|       .|||:...:|:...:.
  Rat   199 PQNPFVQKVKKLLKFNFLDPFFLSVI-----LFP----FLTPVFEAFDITVFPKDVMKFFRTSVE 254

  Fly   257 EALRLRRSKHQE----RNDFINHLLEMQRELD------LSEEDMASHAMTFMFDGLDTTSNSIAH 311
               |::.::.||    |.||:..::..|...|      |::.::.:.::.|:|.|.:|||::::.
  Rat   255 ---RMKENRMQEKVKQRLDFLQLMINSQSSGDKESHQGLTDVEIVAQSIFFIFAGYETTSSALSF 316

  Fly   312 CLLLLGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFNESLRIYPAGGWASKTCTKEY 376
            .|.||..:||.|::|.:|:....|.......|.|:::.||....||:||::|.||...:.|.|:.
  Rat   317 ALYLLATHPDLQKKLQDEIDAALPNKAPVTYDVLVEMEYLDMVLNETLRLFPVGGRLERVCKKDV 381

  Fly   377 ELRGSHHSEPLKLRPGDHVMVPIYALHNDPDLYPEPDVFRPERFLDGGLKNCKQQG-----IFLG 436
            |:.|      :.:..|..||||.:|||.||..:|||:.|.||||      ..|.|.     |:|.
  Rat   382 EING------VFIPKGTVVMVPTFALHKDPKCWPEPEEFCPERF------RKKNQDSINPYIYLP 434

  Fly   437 FGNGPRQCVGMRLGLAMAKAALAAIVQRF 465
            ||||||.|:|||..|...|.||..::|.|
  Rat   435 FGNGPRNCIGMRFALMNMKIALVRVLQNF 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28c1	NP_572752.1	CYP6-like	67..493	CDD:410679	116/426 (27%)
Cyp3a62	NP_001019403.1	CYP3A	67..492	CDD:410743	117/429 (27%)