Protein Alignment Cyp28c1 and CYP3A7-CYP3A51P

DIOPT Version :9

• Sequence 1: NP_001259464.1
• Gene: Cyp28c1 / 32138
• FlyBaseID: FBgn0030339
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001243426.2
• Gene: CYP3A7-CYP3A51P / 100861540
• HGNCID: 51504
• Length: 535
• Species: Homo sapiens
• Alignment Length: 548
• Identity: 138/548 - (25%)
• Similarity: 237/548 - (43%)
• Gaps: 84/548 - (15%)

  Fly     5 LLLGIATLLGAIYAFLVSNFGHWRRRGVTEPRALPLFG---SFPNMIWPRQHFTMDMRDIYMHYR 66
            |||.::.:|  :|.:.....|.:::.|:..|..||..|   ||....|     |.|| :.|..||
Human    13 LLLAVSLIL--LYLYGTRTHGLFKKLGIPGPTPLPFLGNALSFRKGYW-----TFDM-ECYKKYR 69

  Fly    67 NTHSYVGCYLLRAPKLLVLEPRLVYEIYV-SAFSHFENNDASKMVDIAKDRLVALNPFVLEGEEW 130
            ...   |.|..:.|.|.:.:|.::..:.| ..:|.|.|......|...|:.:     .:.|.|||
Human    70 KVW---GIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAI-----SIAEDEEW 126

  Fly   131 RHQRAVFSTLLTNGRIRTTHAIMQRVCLDLCQFIAIKSAGGKDLDCIDLGLRFTGESLFDCVLGI 195
            :..|::.|...|:|:::....|:.:....|.:.:..::..||.:....:...::.:.:.....|:
Human   127 KRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGV 191

  Fly   196 QARTFTDNPLPVVRQNHEMSAENR----GLAIAGAVHGLFPNLP---RWLRPKVFPRSHDRFYGQ 253
            ...:..:...|.|....::...|.    .|:|.     :||.|.   ..|...||||....|..:
Human   192 SIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIK-----VFPFLTPILEALNITVFPRKVISFLTK 251

  Fly   254 MISEAL--RLRRS-KHQERNDFINHLLEMQRELD------LSEEDMASHAMTFMFDGLDTTSNSI 309
            .:.:..  ||:.: ||  |.||:..:::.|...|      ||:.::.:.::.|:|.|.:|||:.:
Human   252 SVKQIKEGRLKETQKH--RVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVL 314

  Fly   310 AHCLLLLGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFNESLRIYPAGGWASKTCTK 374
            :..:..|..:||.|:::.:|:..|.|....|..|.::.|.||....||:||::|......:.|.|
Human   315 SFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKK 379

  Fly   375 EYELRGSHHSEPLKLRPGDHVMVPIYALHNDPDLYPEPDVFRPERFLDGGLKNCKQQGIFLGFGN 439
            :.|:.|      :.:..|..||:|.|.||:||..:.||:.|.||||......|.... |:..||:
Human   380 DVEING------MFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPY-IYTPFGS 437

  Fly   440 GPRQCVGMRLGLAMAKAALAAIVQRFE------------------------VVVSPRTLNGT--E 478
            |||.|:|||..|...|.||..::|.|.                        :|:...:.:.|  :
Human   438 GPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLRFGGLLLTEKPIVLKAESRDETFVD 502

  Fly   479 LDP--------LIFVGVHKGGIWLQFVP 498
            ::|        |.|.|.|....|....|
Human   503 MEPIHMDFLRSLAFQGPHLCFFWELLCP 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28c1	NP_001259464.1	p450	35..487	CDD:299894	127/505 (25%)
CYP3A7-CYP3A51P	NP_001243426.2	p450	39..492	CDD:278495	123/480 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820