Protein Alignment Cyp28c1 and cyp2a6.2

DIOPT Version :10

• Sequence 1: NP_572752.1
• Gene: Cyp28c1 / 32138
• FlyBaseID: FBgn0030339
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001106451.1
• Gene: cyp2a6.2 / 100127628
• XenbaseID: XB-GENE-5892300
• Length: 494
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 117/509 - (22%)
• Similarity: 198/509 - (38%)
• Gaps: 97/509 - (19%)

  Fly     7 LGI--ATLLGAIYAFLVSNFGHWRR--RGVTEPRALPLFGSFPNMIW-PRQHFTMDMRDIYMHYR 66
            ||:  :.:|..|.:|||.:| .|||  |.:..|...||:....||:. ..:.|...:..:...|.
 Frog     3 LGVTWSLILAVIVSFLVYSF-TWRRKLRKINMPPGPPLYPLLGNMLQISAKEFPQSLVKLSEKYG 66

  Fly    67 NTHSYVGCYLLRAPKLLVLEPRLVYEIYVSAFSHFENNDASKM-VDIAKDRLVALNPFVLEGEEW 130
            ...:   .||...|.:::.....:.|..:.....|.....|.: ..:.||..|..:    .||.|
 Frog    67 TVFT---VYLPSKPAVILSGYDCIKEALLDNNESFGARGESPLGYLLFKDYGVIFS----NGERW 124

  Fly   131 RHQRAVFSTLLTN---GRIRTTHAIMQRVCLDLCQFIAIKSAGGKDLD-------------C-ID 178
            :..|....:.|.:   |:......|.:..   .|....:...|...:|             | :.
 Frog   125 KQLRRFSLSCLRDFGMGKKSIEERIQEEA---RCLVEELGKNGDTPMDPTYMLTLAVSNVICTVV 186

  Fly   179 LGLRF--TGESLFDCV--LGIQARTFTDNPLPVVRQNHEMSAENRGLAIAGAVHGLFPN-LPRWL 238
            .|.||  ..|.....:  |.|.:|.|:                    :..|.:..|||| |.|..
 Frog   187 FGERFDYKDEKFMTLISLLKIVSRDFS--------------------SAWGILLNLFPNTLSRLP 231

  Fly   239 RP--KVFPRSHDRFYGQMISEALRLRRSKHQER------NDFIN-HLLEMQRE-----LDLSEED 289
            .|  ::| |:.|:... .::|:|:    .|||.      .|||: .|::|::|     .:...::
 Frog   232 GPPQRLF-RNFDKLKA-FVAESLK----SHQETLNSDCPRDFIDCFLIKMEKEKNNPQTEFHSDN 290

  Fly   290 MASHAMTFMFDGLDTTSNSIAHCLLLLGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSAC 354
            :....:...|.|.:|||.::.:..|:|.:..:..|:..||:..:......|..:..|.:||.:|.
 Frog   291 LFGTVLDLFFAGTETTSITLKYSFLMLLKYTEVTRKAMEEIDNIIGQERCPFYEDRIKMPYTNAV 355

  Fly   355 FNESLR---IYPAGGWASKTCTKEYELRGSHHSEPLKLRPGDHVMVPIY-ALHNDPDLYPEPDVF 415
            .:|..|   |.|.|  .....|.:...||.:       .|.|.::.|:. ::..||..:.:|..|
 Frog   356 IHEIQRMADIVPLG--VPHATTHDIIFRGYN-------IPKDTIIFPLMTSVLKDPKYFNDPKQF 411

  Fly   416 RPERFLDGGLKNCKQQGIFLGFGNGPRQCVGMRLGLAMAKAAL--AAIVQRFEV 467
            .|..|||.. .:.|:...|..|..|.|.|:|.  |||..:..|  .:|:|.|.:
 Frog   412 DPAHFLDEN-GSFKKNDAFQPFSIGKRSCLGE--GLARMEIFLFITSILQAFNL 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28c1	NP_572752.1	CYP6-like	67..493	CDD:410679	98/444 (22%)
cyp2a6.2	NP_001106451.1	cytochrome_P450	65..489	CDD:477761	99/446 (22%)