Protein Alignment rudhira and BCAS3

DIOPT Version :10

• Sequence 1: NP_001368979.1
• Gene: rudhira / 32136
• FlyBaseID: FBgn0266019
• Length: 2162
• Species: Drosophila melanogaster
• Sequence 2: NP_001340073.1
• Gene: BCAS3 / 54828
• HGNCID: 14347
• Length: 958
• Species: Homo sapiens
• Alignment Length: 1102
• Identity: 371/1102 - (33%)
• Similarity: 509/1102 - (46%)
• Gaps: 269/1102 - (24%)

  Fly     1 MSADSPRRHPSGVVGSGIGLGSGSGTGLGSGSTGGSKSGAAVPAIVPPQTVSDRSILDSAIGFIN 65
            |:.|||||                    .|..|||        .:|.||.|:::|.::|.:.|:.
Human     5 MATDSPRR--------------------PSRCTGG--------VVVRPQAVTEQSYMESVVTFLQ 41

  Fly    66 DV---TLANQPVQDPKDTITWARFETCADVSD-PRFGDDWELE--GNAAPPLLLILGYGLGVQVW 124
            ||   ..:..|:.:.|:.|.|.|||. ||::| .|..:..|:.  || .||||:::||..|:|||
Human    42 DVVPQAYSGTPLTEEKEKIVWVRFEN-ADLNDTSRNLEFHEIHSTGN-EPPLLIMIGYSDGMQVW 104

  Fly   125 AIPANGEAVEVLSWRHGVVTALRVLPTPATAAALDENGRADEPVDSFAEKRPLVAFVDGGSAAAS 189
            :||.:|||.|:.|.|||.:.|.|:||.|...|         :..|:|||||||:
Human   105 SIPISGEAQELFSVRHGPIRAARILPAPQFGA---------QKCDNFAEKRPLL----------- 149

  Fly   190 GLLAGSSGLGLGGGGGGVTTVGGSVGGVSGIGVSASAQFSAVNFMSLKTGVQVKTIKFKNAVLDI 254
                            ||....||.|        .|..:..|:..||:||..||:|:||..:.|:
Human   150 ----------------GVCKSIGSSG--------TSPPYCCVDLYSLRTGEMVKSIQFKTPIYDL 190

  Fly   255 QANRSAVVITFHERIAVFDARTLEDRLTITTCYPSPGINPNPIALGPRWLAYAEHKLLHSKRSGG 319
            ..|:..:|:...|:||.||:.|...:..:|:|||.||.|.||||||.|||||||:||:...:|.|
Human   191 HCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPIALGSRWLAYAENKLIRCHQSRG 255

  Fly   320 GCDGEGVPSYTATVLNAAKSLSKGLREFGEQVAAGLTGTTAGSGASSKSSSFDSASGGPDAKQS- 383
            |..|:.:.||||||::|||:|..||...| :|...||||.. ||.:....:..|     ::::|
Human   256 GACGDNIQSYTATVISAAKTLKSGLTMVG-KVVTQLTGTLP-SGVTEDDVAIHS-----NSRRSP 313

  Fly   384 ---GVVTIIDVKHPVKDYSPTSGTPLSSTAGSQGGGDPIVAHFVAHSEALVAMEFDSSGMLLLTA 445
               |::|:||.:      :...|..|.|   .....|.|||||.||.:.:..|.|::|||||:|.
Human   314 LVPGIITVIDTE------TVGEGQVLVS---EDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTT 369

  Fly   446 DRRGHDFHVFRVQPHPVGPSLAAVHHLYVLHRGDTSAKVQHIAFSLDSRWAAVSTLRGTTHVFPI 510
            |..|||||||::..||...|..||||||.||||:|.||||.|.||.|.||..|||||||:|||||
Human   370 DTLGHDFHVFQILTHPWSSSQCAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPI 434

  Fly   511 TPYGGAMGVRTHTSLHVVNKLSRFHRSAGL----------------GADGRSSSP---------- 549
            .||||...||||.|..|||::|||.:||||                ...|.||||
Human   435 NPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHANQQ 499

  Fly   550 -------------------ISHSESTTFVQSLQPYH--------NPTLPPYPRPSVVQPLAQLRQ 587
                               |..|..:..:.|...|:        ||.|.|.|...||.||||::|
Human   500 INTKELIGSFLNVGRAYRLIGISGLSGKLNSQDSYNNFTNNNPGNPRLSPLPSLMVVMPLAQIKQ 564

  Fly   588 PFTLGSPPGSAGLGGGVGGGGVMGSGVSAGGHGVGVGVGSNSQRQRQRLSSLSDDSGKPLSVCSI 652
            |.|||:.....       |..:.|:|.        ..:.:..:.:.....|.|...|....|.:|
Human   565 PMTLGTITKRT-------GPYLFGAGC--------FSIKAPCKVKPPPQISPSKSMGGEFCVAAI 614

  Fly   653 FAKSRSWLLEPPMATREQPHRVQRKAVDSLFVMAGHGALIQYDLDTKLASHVAKEKICDDTPIEL 717
            |..||||........||:....| ..|:||::::.:|.|:::.::.:..|  ...||.||||:|:
Human   615 FGTSRSWFANNAGLKREKDQSKQ-VVVESLYIISCYGTLVEHMMEPRPLS--TAPKISDDTPLEM 676

  Fly   718 EVEARAQWNLGRRKDGSQEIAPPLGLDNWLIK------------------------DRHA---SL 755
            ....||.|.|.|....: |:.||...::.|:.                        .||.   ||
Human   677 MTSPRASWTLVRTPQWN-ELQPPFNANHPLLLAADAVQYYQFLLAGLVPPGSPGPITRHGSYDSL 740

  Fly   756 LLDSANQFDDPDERTESWLAQVEIITHAGPHRRLWMGPQFVFKNYNTPSGSNLNHVDAEAVEIGV 820
            ..|.:.|.|      |.||:||||:||.||||||||||||.||..: |||           :..|
Human   741 ASDHSGQED------EEWLSQVEIVTHTGPHRRLWMGPQFQFKTIH-PSG-----------QTTV 787

  Fly   821 SKTTTTTLPSTAASSA-----------LGLGTI-IGKDRSSPLNMPLSAATSVGGAGIGSS-AVT 872
            ..::::.|.|...|..           |.|.:: |...||.|::||            ||| .|:
Human   788 ISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRIQPVRSDPVSMP------------GSSRPVS 840

  Fly   873 GRSGAGVPVLIESGSYSSIEQSPKLM-------DRFRHGHLDSDYGHGDTRLKEDLADAMRESPS 930
            .|.|....:...||::   ::|..|:       :.|...|: |...|.:..|:|.|||||.||||
Human   841 DRRGVSTVIDAASGTF---DRSVTLLEVCGSWPEGFGLRHM-SSMEHTEEGLRERLADAMAESPS 901

  Fly   931 TAAARRETTAASVDQAAPPCGDHLATGASPASADLLAAGAGGSASSNCDNVCYYDALAEHES 992
                 |:...:         |..|....|..:....:....||...|.|.  |...|..:||
Human   902 -----RDVVGS---------GTELQREGSIETLSNSSGSTSGSIPRNFDG--YRSPLPTNES 947

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rudhira	NP_001368979.1	BCAS3	635..818	CDD:463605	68/209 (33%)
BCAS3	NP_001340073.1	BCAS3	611..783	CDD:463605	63/182 (35%)