Protein Alignment CG1578 and dph6

DIOPT Version :10

• Sequence 1: NP_572749.2
• Gene: CG1578 / 32135
• FlyBaseID: FBgn0030336
• Length: 901
• Species: Drosophila melanogaster
• Sequence 2: NP_595310.1
• Gene: dph6 / 2540717
• PomBaseID: SPBC577.12
• Length: 606
• Species: Schizosaccharomyces pombe
• Alignment Length: 751
• Identity: 235/751 - (31%)
• Similarity: 331/751 - (44%)
• Gaps: 233/751 - (31%)

  Fly     1 MRVVAMVSGGKDSCYNMMQCVAEGHEIVALANLHPKD-RDELDSFMYQTVGHMGIEILASAMGLP 64
            |:|:.::|||||||:|:|.||:.|||:||||||||:| :||:||||||:|||..|.:.|....||
pombe     1 MKVLGLISGGKDSCFNLMHCVSLGHEVVALANLHPEDGKDEIDSFMYQSVGHDVIPLYAECFDLP 65

  Fly    65 LYRRETKGKSTQTGKQYVPTDDDEVEDLYSLLE-TCKHELQVDAVAVGAILSDYQRVRVENVCSR 128
            |||.:..|:|......|..|:.||.||||.|:: ...:...::||:.|||||.|||.||||||.|
pombe    66 LYREKIGGQSINQNLDYQFTEKDETEDLYRLIKRVLTNHPDLEAVSTGAILSTYQRTRVENVCKR 130

  Fly   129 LNLISLAYLWRRDQTELLQEMIDCQVHAIIIKVAALGLVPDRHLGKSLREMQPHLLKMRDKYGLN 193
            |.|.||::||::||.:||.:|:...::||:|||||:||. .:.|||||.|||..||.:..|:.|:
pombe   131 LGLKSLSFLWQKDQEKLLNDMVVSGLNAILIKVAAIGLT-RKDLGKSLAEMQDKLLTLNKKFELH 194

  Fly   194 VCGEGGEYETFTLDCPLFRQRIVVEDIQTIISSADPICPVGYINFTKLTLQPKEAAGAASSGGNE 258
            .|||||||||..||||||::|||:.|.:.:..|:..:|   |:. .|..::.|
pombe   195 PCGEGGEYETLVLDCPLFKKRIVLTDKEVVEHSSGEVC---YLK-VKACVKDK------------ 243

  Fly   259 VVFVKRSLDYISDLNESTYSDLSDPDFSETEL--ELIEKETRLRESLSQSELISRSNSFGRHLAA 321
                                    |::....|  ||:..|..|.|..|             |:..
pombe   244 ------------------------PEWQPISLKSELVPNEELLGEEYS-------------HIYH 271

  Fly   322 TASSPIPIVTKSASVDEPTAAAAPILGGVGGPPICSTSACASMLLTTTADGLSSLASSQSQGGGH 386
            |.|....::...   :|...:..||                         .|...|..|.:|...
pombe   272 TISKKYELIDDQ---EETPTSLIPI-------------------------PLRESAFQQKKGSFL 308

  Fly   387 GLGSSTAAVCGSLSLAISSLGLSANTCCHPGGAGGGGGVGIGVGAGAGAGAPSATTQPPSPLKYE 451
            .|| :..|..||
pombe   309 VLG-NVVATKGS----------------------------------------------------- 319

  Fly   452 REFRPLANEARAAINAKGWMWLAGIQGSGTEGIEQGMQQALDTLRDLCQAKGYDLQDLCYVTLYV 516
              :.....||.:|||                           .|.:|....||..:::.:||:.:
pombe   320 --YNTFQGEAESAIN---------------------------NLNELLGTYGYSNKNVYFVTVIL 355

  Fly   517 RSIGEYPLLNRVYHRAFDFHNPPTRVCVECPLPDGCHVVMEAIAYRQPVAGTISSAEERDREGEE 581
            .|:.::...|.||::.|||.|||:|.||..||.....:||..|.                  |:.
pombe   356 SSMSKFAEFNSVYNKYFDFTNPPSRSCVAAPLASEYRIVMSCIV------------------GDV 402

  Fly   582 TAAALLNGRRNTMHVQGISHWAPANIGPYSQSTRIGDITYISGQIALVPGSMTIIEGGIRPQCKL 646
            |       .:..:||||.|:||||||||||||.....:.:|||||.|:|..|.:.......:..|
pombe   403 T-------EKRALHVQGQSYWAPANIGPYSQSICANGVVFISGQIGLIPSVMELKLHDKIFEMVL 460

  Fly   647 TLRHISRIAKAMNAHGQLRDVVHGICFVTHPAFIGEAR------RQWERRTTN---------AIM 696
            .|:|.:|:||||.. |.|         :...|::.::|      :.|...|.|         |::
pombe   461 ALQHANRVAKAMRV-GSL---------IACLAYVCDSRDADCVVKIWSEYTKNTGESSPVLVALV 515

  Fly   697 DYIVLPALPREALVEWQVWAHTHNDRFDYEETGCSV 732
            |     ||||.|.||||:.         |.::.|.|
pombe   516 D-----ALPRNASVEWQLL---------YNDSSCDV 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1578	NP_572749.2	AANH_PF0828-like	2..215	CDD:467498	117/214 (55%)
		eu_AANH_C_1	465..561	CDD:100012	26/95 (27%)
		eu_AANH_C_2	610..716	CDD:100013	38/120 (32%)
dph6	NP_595310.1	AANH_PF0828-like	2..216	CDD:467498	117/214 (55%)
		eu_AANH_C_1	301..399	CDD:100012	35/180 (19%)
		eu_AANH_C_2	424..527	CDD:100013	36/117 (31%)