Protein Alignment Hsc70-3 and hscA

DIOPT Version :10

• Sequence 1: NP_511132.2
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_417021.1
• Gene: hscA / 944885
• ECOCYCID: EG12130
• Length: 616
• Species: Escherichia coli
• Alignment Length: 625
• Identity: 234/625 - (37%)
• Similarity: 363/625 - (58%)
• Gaps: 49/625 - (7%)

  Fly    14 GLSLGEEKKEKDKELGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIG 78
            |||....::.      ...|||||||.|.|...::|:.|.:|:.:|..:.||.|.:...|.. :|
E. coli    10 GLSAAPHQRR------LAAGIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHS-VG 67

  Fly    79 DAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKV-VEKNSKPHISVDTSQGAKVFAP 142
            ..|:.....:..||:...|||:||..:|  :|......|::. ..:|..|  .::|:.|  :..|
E. coli    68 YDARTNAALDTANTISSVKRLMGRSLAD--IQQRYPHLPYQFQASENGLP--MIETAAG--LLNP 126

  Fly   143 EEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAI 207
            ..:||.:|..:...|...|..::...|:||||||:|||||.||||..:|||.|:|::||||||||
E. coli   127 VRVSADILKALAARATEALAGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAI 191

  Fly   208 AYGLDKKEGEKNVL-VFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYK 271
            |||||  .|::.|: |:||||||||:|:|.:..|||||:||.||:.|||:|||..:.|:.    :
E. coli   192 AYGLD--SGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYI----R 250

  Fly   272 KKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFR 336
            ::.|...|.|||..::|......||.|||.:..|.:.:.. ::|:     ::|.:|.||...|.:
E. coli   251 EQAGIPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAG-WQGE-----ISREQFNELIAPLVK 309

  Fly   337 STLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQ 401
            .||...::.|:||.:...:|.|:|:||||||:|.|::.|.:|| |:.|...|:||:.||.|||:|
E. coli   310 RTLLACRRALKDAGVEADEVLEVVMVGGSTRVPLVRERVGEFF-GRPPLTSIDPDKVVAIGAAIQ 373

  Fly   402 AGVLSGEQDTDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVY 466
            |.:|.|.:....::||||.||::|:||:||::.|:|||||.||..::|.|:|..|.|..::|.|.
E. coli   374 ADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVM 438

  Fly   467 EGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQN 531
            :|||.:.:|...|.:|.|.|||..|.|...|.|:|::||:|:|.|:|.:|.||.:..|.:.....
E. coli   439 QGERELVQDCRSLARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYG 503

  Fly   532 RLTPEDIDRMIRDAEKFADEDKKLK----ERVESRNELESYAYSL----------KNQIGDKDKL 582
             ||..:|..||:|:..:|::|.|.:    ::||:...|||...:|          :.|:  .|..
E. coli   504 -LTDSEIASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQV--IDDA 565

  Fly   583 GAKLSDDEKNKLESAIDESIKWLEQNPDADPEEYKKQKKD 622
            .|.||:..:.....||:::||    |.|...:::..::.|
E. coli   566 AAHLSEVAQGDDVDAIEQAIK----NVDKQTQDFAARRMD 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_511132.2	PTZ00009	32..643	CDD:240227	231/607 (38%)
hscA	NP_417021.1	hscA	1..616	CDD:235360	234/625 (37%)