Protein Alignment Hsc70-3 and ECM10

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_010884.1
• Gene: ECM10 / 856682
• SGDID: S000000756
• Length: 644
• Species: Saccharomyces cerevisiae
• Alignment Length: 589
• Identity: 295/589 - (50%)
• Similarity: 392/589 - (66%)
• Gaps: 18/589 - (3%)

  Fly    31 VIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFD 95
            |||||||||.|.|.:.:.....||.|.:|:|.|||.||||.|||||:|:.||.|...|.|||:|.
Yeast    29 VIGIDLGTTNSAVAIMEGKVPRIIENAEGSRTTPSVVAFTKDGERLVGEPAKRQSVINSENTLFA 93

  Fly    96 AKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAY 160
            .||||||.:.|..||.||...|||:| |:|.....|:...  :.::|.:|...:|.|||||||||
Yeast    94 TKRLIGRRFEDAEVQRDINQVPFKIV-KHSNGDAWVEARN--RTYSPAQIGGFILNKMKETAEAY 155

  Fly   161 LGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDL 225
            |.|.|.:|||||||||||||||||||||.|.||.|:|::|||||||:||||||.| .|.:.||||
Yeast   156 LAKSVKNAVVTVPAYFNDAQRQATKDAGQIIGLNVLRVVNEPTAAALAYGLDKSE-PKVIAVFDL 219

  Fly   226 GGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRR 290
            ||||||:|:|.||||:|||.:|||||||||||||..::...|..:||:.|.|:..|..|||::|.
Yeast   220 GGGTFDISILDIDNGIFEVKSTNGDTHLGGEDFDIYLLQEIISHFKKETGIDLSNDRMAVQRIRE 284

  Fly   291 EVEKAKRALSGSHQVRIEIESFFEGD-----DFSETLTRAKFEELNLDLFRSTLKPVQKVLEDAD 350
            ..||||..||.:....|.: .|...|     ......:|.:.|.:...|...|:.||:|.|:||.
Yeast   285 AAEKAKIELSSTLSTEINL-PFITADAAGPKHIRMPFSRVQLENITAPLIDRTVDPVKKALKDAR 348

  Fly   351 MNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDAIV 415
            :...|:.:::||||.:|:|||...||..| ||:.|:.:|||||||.|||:||.|||||. || ::
Yeast   349 ITASDISDVLLVGGMSRMPKVADTVKKLF-GKDASKAVNPDEAVALGAAIQAAVLSGEV-TD-VL 410

  Fly   416 LLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLG 480
            ||||.||::||||:|||.|||||||:.||.||||:||||:..|.:|.::|::|||.:.|||.|:|
Yeast   411 LLDVTPLSLGIETLGGVFTKLIPRNSTIPNKKSQIFSTAASGQTSVEVKVFQGERELVKDNKLIG 475

  Fly   481 KFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDA 545
            .|.|.||||||:|.|||||:|:||||||:.|||:|..: :|:..:.....:.|:..:||||:.:|
Yeast   476 NFTLAGIPPAPKGTPQIEVTFDIDANGIINVSAKDLAS-HKDSSITVAGASGLSDTEIDRMVNEA 539

  Fly   546 EKFADEDKKLKERVESRNELESYAYSLKNQI----GDKDKLGAKLSDDEKNKLESAIDESIKWLE 606
            |::.::|:..:..:|:.|:.:..|...:|.|    |..||..::...|:.:.|...:..|....|
Yeast   540 ERYKNQDRARRNAIETANKADQLANDTENSIKEFEGKLDKTDSQRLKDQISSLRELVSRSQAGDE 604

  Fly   607 QNPD 610
            .|.|
Yeast   605 VNDD 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	198/376 (53%)
		PTZ00009	32..643	CDD:240227	294/588 (50%)
ECM10	NP_010884.1	dnaK	29..644	CDD:234715	295/589 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810