Protein Alignment Hsc70-3 and SSZ1

DIOPT Version :10

• Sequence 1: NP_511132.2
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_011931.2
• Gene: SSZ1 / 856461
• SGDID: S000001106
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 549
• Identity: 153/549 - (27%)
• Similarity: 259/549 - (47%)
• Gaps: 74/549 - (13%)

  Fly    31 VIGIDLGTTYSCVGVYKNGR--VEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTV 93
            ||||..|.|.|.: .|.|.:  |::|||..|.|..||.:::..:.| ..|..|..||..||:||:
Yeast     5 VIGITFGNTSSSI-AYINPKNDVDVIANPDGERAIPSALSYVGEDE-YHGGQALQQLIRNPKNTI 67

  Fly    94 FDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQG-AKVFAPEEISAMVLGKMKETA 157
            .:.:..||..:...:|.......|  .||.:.|....:...:| .:....:|:.:..|.::|..|
Yeast    68 INFRDFIGLPFDKCDVSKCANGAP--AVEVDGKVGFVISRGEGKEEKLTVDEVVSRHLNRLKLAA 130

  Fly   158 EAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLD-KKEGEKNVL 221
            |.|:|..|..||:|||..|::.|:.|.|.:....|||:::.||||:||.:|:... ..|.:.||:
Yeast   131 EDYIGSAVKEAVLTVPTNFSEEQKTALKASAAKIGLQIVQFINEPSAALLAHAEQFPFEKDVNVV 195

  Fly   222 VFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQ 286
            |.|.||...|.:::.:.||:|.::||..|..|||::.|..::::|...::||...:.||:.|::.
Yeast   196 VADFGGIRSDAAVIAVRNGIFTILATAHDLSLGGDNLDTELVEYFASEFQKKYQANPRKNARSLA 260

  Fly   287 KLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADM 351
            ||:......|:.||.:....|.|:|..:|.|:..::.|.::|.:...:|......|..|:..|::
Yeast   261 KLKANSSITKKTLSNATSATISIDSLADGFDYHASINRMRYELVANKVFAQFSSFVDSVIAKAEL 325

  Fly   352 NKKDVHEIVLVGGSTRIPKVQQLVK-------DFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQ 409
            :..|:..::|.||.:..||:...::       :..|.:..:...||:|..|.|||:||.::| :.
Yeast   326 DPLDIDAVLLTGGVSFTPKLTTNLEYTLPESVEILGPQNKNASNNPNELAASGAALQARLIS-DY 389

  Fly   410 DTDAI------VLLDVNPLTMGIETVG--GVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVY 466
            |.|.:      |:::...|...|..:|  |....::...|..|.:|......|..:   ..|.||
Yeast   390 DADELAEALQPVIVNTPHLKKPIGLIGAKGEFHPVLLAETSFPVQKKLTLKQAKGD---FLIGVY 451

  Fly   467 EGERPMTKDNHLLGKFDLTGIPPAPR----------------------------------GIPQ- 496
            ||      |:|:..|    .:.|.|:                                  ||..
Yeast   452 EG------DHHIEEK----TLEPIPKEENAEEDDESEWSDDEPEVVREKLYTLGTKLMELGIKNA 506

  Fly   497 --IEVSFEIDANGILQVSAEDKGTGNKEK 523
              :|:.|.|:.:|.|:|:|.|..|||..|
Yeast   507 NGVEIIFNINKDGALRVTARDLKTGNAVK 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_511132.2	PTZ00009	32..643	CDD:240227	152/548 (28%)
SSZ1	NP_011931.2	ASKHA_NBD_HSP70_ScSsz1p-like	4..386	CDD:466830	117/384 (30%)