Protein Alignment Hsc70-3 and SSE1

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_015219.1
• Gene: SSE1 / 855998
• SGDID: S000006027
• Length: 693
• Species: Saccharomyces cerevisiae
• Alignment Length: 659
• Identity: 186/659 - (28%)
• Similarity: 317/659 - (48%)
• Gaps: 85/659 - (12%)

  Fly    28 LGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENT 92
            :.|..|:|||...|.:.|.:|..::|:.|:..||.|||.|.| ....|.:|:..||:.|:|.:||
Yeast     1 MSTPFGLDLGNNNSVLAVARNRGIDIVVNEVSNRSTPSVVGF-GPKNRYLGETGKNKQTSNIKNT 64

  Fly    93 VFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAK-VFAPEEISAMVLGKMKET 156
            |.:.||:||.::...:.:.:.|.|..|:||.:.|...:.....|.| ||:..:::||.:.|:|:|
Yeast    65 VANLKRIIGLDYHHPDFEQESKHFTSKLVELDDKKTGAEVRFAGEKHVFSATQLAAMFIDKVKDT 129

  Fly   157 AEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGL---DKKEGEK 218
            .:......:|...:.||.::.:.||....||..||||..:||:|:.|||.::||:   |..|||:
Yeast   130 VKQDTKANITDVCIAVPPWYTEEQRYNIADAARIAGLNPVRIVNDVTAAGVSYGIFKTDLPEGEE 194

  Fly   219 N---VLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRK 280
            .   |...|:|..::..|::....|..:|:.|..|.|.||.|||..:.:||...:|.|...|||:
Yeast   195 KPRIVAFVDIGHSSYTCSIMAFKKGQLKVLGTACDKHFGGRDFDLAITEHFADEFKTKYKIDIRE 259

  Fly   281 DNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKV 345
            :.:|..::....||.|:.||.:......:||.....|.|..|:|.:.|||...|.....:||.|.
Yeast   260 NPKAYNRILTAAEKLKKVLSANTNAPFSVESVMNDVDVSSQLSREELEELVKPLLERVTEPVTKA 324

  Fly   346 LEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQD 410
            |..|.::.::|..:.::||:||||.::|.:.:.| ||..|..:|.|||:|.|||....:.|....
Yeast   325 LAQAKLSAEEVDFVEIIGGTTRIPTLKQSISEAF-GKPLSTTLNQDEAIAKGAAFICAIHSPTLR 388

  Fly   411 TDAIVLLDVNPLT--------------MGIETVGGVM--TKLIPRNTVIPTKKSQVFSTASDNQH 459
            .......|::|.:              |.:...|...  ||||..|      ::..||.|:  .:
Yeast   389 VRPFKFEDIHPYSVSYSWDKQVEDEDHMEVFPAGSSFPSTKLITLN------RTGDFSMAA--SY 445

  Fly   460 TVTIQVYEGERPMTKDNHLLGKFDLTGI--PPAPRGIPQIEVSFEIDANGILQV----SAEDKGT 518
            |...|:    .|.|.:.  :..:::||:  |.....:| :::....|.:|:..:    :.||...
Yeast   446 TDITQL----PPNTPEQ--IANWEITGVQLPEGQDSVP-VKLKLRCDPSGLHTIEEAYTIEDIEV 503

  Fly   519 GNKEKIVITNDQNRLTPEDIDRMIRDAEKFADED-------------KKLKERVESRNE------ 564
              :|.|.:..|    .|||.::..:...|...:|             |||.|.:|..||
Yeast   504 --EEPIPLPED----APEDAEQEFKKVTKTVKKDDLTIVAHTFGLDAKKLNELIEKENEMLAQDK 562

  Fly   565 -----------LESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWL-EQNPDADPEEYK 617
                       ||.|.|:|:.::  :::.....||.||.||:..::::.:|| ::..|:...:|.
Yeast   563 LVAETEDRKNTLEEYIYTLRGKL--EEEYAPFASDAEKTKLQGMLNKAEEWLYDEGFDSIKAKYI 625

  Fly   618 KQKKDLEAI 626
            .:.::|.::
Yeast   626 AKYEELASL 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	130/380 (34%)
		PTZ00009	32..643	CDD:240227	185/655 (28%)
SSE1	NP_015219.1	HSP70	4..644	CDD:394970	185/656 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810