Protein Alignment Hsc70-3 and SSC1

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_012579.1
• Gene: SSC1 / 853503
• SGDID: S000003806
• Length: 654
• Species: Saccharomyces cerevisiae
• Alignment Length: 638
• Identity: 310/638 - (48%)
• Similarity: 425/638 - (66%)
• Gaps: 22/638 - (3%)

  Fly    23 EKDKELGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTT 87
            :..|..|:|||||||||.|.|.:.:....:||.|.:|:|.|||.||||.:||||:|..||.|...
Yeast    24 QSTKVQGSVIGIDLGTTNSAVAIMEGKVPKIIENAEGSRTTPSVVAFTKEGERLVGIPAKRQAVV 88

  Fly    88 NPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGK 152
            |||||:|..||||||.:.|..||.|||..|:|:| |:|.....|:..  .:.::|.:|...||.|
Yeast    89 NPENTLFATKRLIGRRFEDAEVQRDIKQVPYKIV-KHSNGDAWVEAR--GQTYSPAQIGGFVLNK 150

  Fly   153 MKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGE 217
            |||||||||||.|.:|||||||||||:|||||||||.|.||.|:|::|||||||:||||:|.: .
Yeast   151 MKETAEAYLGKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAYGLEKSD-S 214

  Fly   218 KNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDN 282
            |.|.||||||||||:|:|.||||||||.:|||||||||||||..::...:..:|.:.|.|:..|.
Yeast   215 KVVAVFDLGGGTFDISILDIDNGVFEVKSTNGDTHLGGEDFDIYLLREIVSRFKTETGIDLENDR 279

  Fly   283 RAVQKLRREVEKAKRALSGSHQVRIEIESFFEGD-----DFSETLTRAKFEELNLDLFRSTLKPV 342
            .|:|::|...||||..||.:....|.: .|...|     ..:...:||:||.|...|.:.|:.||
Yeast   280 MAIQRIREAAEKAKIELSSTVSTEINL-PFITADASGPKHINMKFSRAQFETLTAPLVKRTVDPV 343

  Fly   343 QKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSG 407
            :|.|:||.::..|:.|::||||.:|:|||.:.||..| ||:||:.:|||||||.|||||..||||
Yeast   344 KKALKDAGLSTSDISEVLLVGGMSRMPKVVETVKSLF-GKDPSKAVNPDEAVAIGAAVQGAVLSG 407

  Fly   408 EQDTDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPM 472
            |. || ::||||.||::||||:|||.|:||||||.|||||||:||||:..|.:|.|:|::|||.:
Yeast   408 EV-TD-VLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAAGQTSVEIRVFQGEREL 470

  Fly   473 TKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPED 537
            .:||.|:|.|.|.||||||:|:|||||:|:|||:||:.|||.||.| ||:..:.....:.|:..:
Yeast   471 VRDNKLIGNFTLAGIPPAPKGVPQIEVTFDIDADGIINVSARDKAT-NKDSSITVAGSSGLSENE 534

  Fly   538 IDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQI----GDKDKLGAKLSDDEKNKLESAI 598
            |::|:.|||||..:|:..|:.:|:.|:.:..|...:|.:    |..||..|:...|:...|:
Yeast   535 IEQMVNDAEKFKSQDEARKQAIETANKADQLANDTENSLKEFEGKVDKAEAQKVRDQITSLK--- 596

  Fly   599 DESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQGAGGAPPPEGGDDAD 651
             |.:..::...:.:.||.|.:.::|:.....:..:||:..........|::|:
Yeast   597 -ELVARVQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNNNNNGNNAE 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	203/378 (54%)
		PTZ00009	32..643	CDD:240227	305/619 (49%)
SSC1	NP_012579.1	dnaK	30..633	CDD:234715	306/615 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810