Protein Alignment Hsc70-3 and SSE2

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_009728.1
• Gene: SSE2 / 852467
• SGDID: S000000373
• Length: 693
• Species: Saccharomyces cerevisiae
• Alignment Length: 641
• Identity: 178/641 - (27%)
• Similarity: 308/641 - (48%)
• Gaps: 49/641 - (7%)

  Fly    28 LGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENT 92
            :.|..|:|||...|.:.|.:|..::::.|:..||.|||.|.| ....|.:|::.|.:.|:|.:||
Yeast     1 MSTPFGLDLGNNNSVLAVARNRGIDVVVNEVSNRSTPSLVGF-GPRNRYLGESGKTKQTSNVKNT 64

  Fly    93 VFDAKRLIGREWSDTNVQHDIKFFPFKVVE-KNSKPHISVDTSQGAKVFAPEEISAMVLGKMKET 156
            |.:.||:||.::.|.....:.|||..|:|: ||.|..:.|:......||:..:::||.:.|:|.|
Yeast    65 VENLKRIIGLKFKDPEFDIENKFFTSKLVQLKNGKVGVEVEFGGKTHVFSATQLTAMFIDKVKHT 129

  Fly   157 AEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDK------KE 215
            .:......:|...:.||.::::.||....||..||||..:||:|:.||||::||:.|      :|
Yeast   130 VQEETKSSITDVCLAVPVWYSEEQRYNIADAARIAGLNPVRIVNDVTAAAVSYGVFKNDLPGPEE 194

  Fly   216 GEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRK 280
            ..:.:.:.|:|..|:..|::....|..:|:.|..|.|.||.|||:.:.:||...:|.|...||||
Yeast   195 KPRIIGLVDIGHSTYTCSIMAFRKGEMKVLGTAYDKHFGGRDFDRAITEHFADQFKDKYKIDIRK 259

  Fly   281 DNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKV 345
            :.:|..::....||.|:.||.:......:||..:..|.|..|:|.:.|||...|.:....|:...
Yeast   260 NPKAYNRILIAAEKLKKVLSANTTAPFSVESVMDDIDVSSQLSREELEELVEPLLKRVTYPITNA 324

  Fly   346 LEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQD 410
            |..|.:...|:..:.::||:||||.:::.:.|.| ||..|..:|.|||||.|||....:.|....
Yeast   325 LAQAKLTVNDIDFVEIIGGTTRIPVLKKSISDVF-GKPLSSTLNQDEAVAKGAAFICAIHSPTLR 388

  Fly   411 TDAIVLLDVNPLTMGIETVGGV----MTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERP 471
            .......|::|.::.......|    ..::.|.|:..|:.|........|.....   ||.....
Yeast   389 VRPFKFEDIDPYSVSYTWDKQVDDEDRLEVFPANSSYPSTKLITLHRTGDFSMKA---VYTHPSK 450

  Fly   472 MTK-DNHLLGKFDLTGIP-PAPRGIPQIEVSFEIDANGILQV----SAED--------------- 515
            :.| .:..:.|:..||:. |..:....::|....|.:|:..:    :.||
Yeast   451 LPKGTSTTIAKWSFTGVKVPKDQDFIPVKVKLRCDPSGLHIIENAYTTEDITVQEPVPLPEDAPE 515

  Fly   516 ---------KGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYS 571
                     ..|..|:.:.:|.....|.|.:::.:|....:..::||.:.|..:.:|.||.|.|:
Yeast   516 DAEPQFKEVTKTIKKDVLGMTAKTFALNPVELNDLIEKENELRNQDKLVAETEDRKNALEEYIYT 580

  Fly   572 LKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWL-EQNPDADPEEYKKQKKDLEAI 626
            |:.::.|:....|  ||.||.||::.:..:..|| ....|:...:|..:.::|.::
Yeast   581 LRAKLDDEYSDFA--SDAEKEKLKNMLATTENWLYGDGDDSTKAKYIAKYEELASL 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	129/380 (34%)
		PTZ00009	32..643	CDD:240227	177/637 (28%)
SSE2	NP_009728.1	HSP70	4..644	CDD:394970	177/638 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810