DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsc70-3 and AT3G09440

DIOPT Version :9

Sequence 1:	NP_001285139.1	Gene:	Hsc70-3 / 32133	FlyBaseID:	FBgn0001218	Length:	656	Species:	Drosophila melanogaster
Sequence 2:	NP_001189847.1	Gene:	AT3G09440 / 820102	AraportID:	AT3G09440	Length:	649	Species:	Arabidopsis thaliana

Alignment Length:	630	Identity:	399/630 - (63%)
Similarity:	499/630 - (79%)	Gaps:	8/630 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTV 93
            |..||||||||||||||:::.||||||||||||.|||||||| |.|||||||||||:..||.|||
plant     7 GPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFT-DSERLIGDAAKNQVAMNPINTV 70

  Fly    94 FDAKRLIGREWSDTNVQHDIKFFPFKVVE-KNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETA 157
            |||||||||.::|::||.|||.:||.:.. ...||.|.|:.....|.|:.||||:|:|.||:|.|
plant    71 FDAKRLIGRRFTDSSVQSDIKLWPFTLKSGPAEKPMIVVNYKGEDKEFSAEEISSMILIKMREIA 135

  Fly   158 EAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKE---GEKN 219
            |||||..:.:|||||||||||:||||||||||||||.||||||||||||||||||||.   ||||
plant   136 EAYLGTTIKNAVVTVPAYFNDSQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKATSVGEKN 200

  Fly   220 VLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRA 284
            ||:|||||||||||||||:.|:|||.||.|||||||||||.|:::||::.:|:|..|||..:.||
plant   201 VLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKNKKDISGNPRA 265

  Fly   285 VQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDA 349
            :::||...|:|||.||.:.|..|||:|.|:|.||...:|||:|||||:||||..::||:|.|.||
plant   266 LRRLRTACERAKRTLSSTAQTTIEIDSLFDGIDFYAPITRARFEELNIDLFRKCMEPVEKCLRDA 330

  Fly   350 DMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGE--QDTD 412
            .|:|..:.::|||||||||||||||:.|||.|||..:.|||||||||||||||.:||||  :...
plant   331 KMDKNSIDDVVLVGGSTRIPKVQQLLVDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGNEKVQ 395

  Fly   413 AIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNH 477
            .::||||.||::|:||.|||||.||.|||.|||||.|||||.||||..|.||||||||..||||:
plant   396 DLLLLDVTPLSLGLETAGGVMTVLIQRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERARTKDNN 460

  Fly   478 LLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMI 542
            |||||:|:||||||||:|||.|.|:|||||||.||||||.||.|.||.||||:.||:.::|::|:
plant   461 LLGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGQKNKITITNDKGRLSKDEIEKMV 525

  Fly   543 RDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQ 607
            ::|||:..||::.|::|:::|.||:|||:::|.|.| :|:|.||:.|:|.|:|.:|:.:|:|||.
plant   526 QEAEKYKSEDEEHKKKVDAKNALENYAYNMRNTIRD-EKIGEKLAGDDKKKIEDSIEAAIEWLEA 589

  Fly   608 NPDADPEEYKKQKKDLEAIVQPVIAKLYQGAGGAPPPEGGDDADL 652
            |..|:.:|::.:.|:||:|..|:|||:|||.....|..||.|.|:
plant   590 NQLAECDEFEDKMKELESICNPIIAKMYQGGEAGGPAAGGMDEDV 634

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	255/377 (68%)
Hsc70-3	NP_001285139.1	PTZ00009	32..643	CDD:240227	393/616 (64%)
AT3G09440	NP_001189847.1	PTZ00009	5..649	CDD:240227	399/630 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.730