Protein Alignment Hsc70-3 and hspa12a

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: XP_017207164.1
• Gene: hspa12a / 751725
• ZFINID: ZDB-GENE-031001-1
• Length: 671
• Species: Danio rerio
• Alignment Length: 654
• Identity: 147/654 - (22%)
• Similarity: 233/654 - (35%)
• Gaps: 207/654 - (31%)

  Fly    19 EEKKEKDKELGTVIGIDLGTTYS-----------CVGVYKNGRVEIIANDQG--NRITPSYVAFT 70
            ||.:........|:.||.|||.|           |:...:...    ..|.|  |:.||:.:..|
Zfish    44 EENEPPRHHFVVVVAIDFGTTSSGYAYAFTKEPECIHTMRRWE----GGDPGVSNQKTPTTILLT 104

  Fly    71 ADGE-RLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDT- 133
            .|.: ...|.||:        :...|......::|        :....|| ::.::..::|:||
Zfish   105 PDKKFHSFGYAAR--------DFYHDLDPTESKQW--------LYLEKFK-MKLHTTANLSIDTD 152

  Fly   134 ---SQGAKVFAPEEISAMVLGKMKETAEAYL----GKKVTHA----VVTVPAYFNDAQRQATKDA 187
               :.|.||.| .:|.|..|...||.|...|    |.:..:|    |:||||.:....:|..::|
Zfish   153 LHAANGKKVKA-LDIFAYALAFFKEQALKELSDQAGAEFDNADVRWVITVPAIWKMPAKQFMREA 216

  Fly   188 GVIAGLQVMR-------IINEPTAAAI----------------------------AYGL------ 211
            ...|.| |.|       |..||.||:|                            ..|:
Zfish   217 AYKAAL-VTRENPDQLIIALEPEAASIYCRKLRLHQMVDLGSKTALNGYSPTDNAGVGMTQAKEH 280

  Fly   212 ---------------------DKKEGEKNVLVFDLGGGTFDVSL--LTIDNGVFEVV--ATNGDT 251
                                 :..||::.|:| |.||||.|:::  :.:..|..:.:  |:.|..
Zfish   281 VRRNRQSRTFLVENVIGELWSELAEGDRYVVV-DCGGGTVDLTVHQIRLPEGHLKELYKASGGPY 344

  Fly   252 HLGGEDFDQRVMDHFIKLYKKKKGKDI-----RKDNRAVQKLRREVEKAKRALSGSHQVRIEIE- 310
            ...|.|::      |.||..|..|:|.     .|...|...|....|..|||.:......:.|.
Zfish   345 GSIGIDYE------FEKLLCKIFGQDFIDQFKIKRPAAWVDLMIAFESRKRAATPDRSNPLNINL 403

  Fly   311 --SF------FEGDDFSETLTRAKFE----------ELNLDLFRSTLKP-----VQKVLEDADMN 352
              ||      |.|......|.::..:          .::.|...:..||     :|.:.|..|..
Zfish   404 PFSFIDYYKKFRGHSVEHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDHIIQHLTELFDRP 468

  Fly   353 K-KDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAG-VLSGEQDTDAIV 415
            : .|:..:.||||....|.:||.|::...|:  ||.|.|.:.   |..:..| ||.|..  .:|:
Zfish   469 EVTDIKFLFLVGGFAESPLLQQAVQNMLQGR--SRIIIPHDV---GLTILKGAVLFGLD--PSII 526

  Fly   416 LLDVNPLTMGIETVGGVMTKLI-----PR---------------NTVIPTKKS--------QVFS 452
            .:..:|||.|:    ||:.:.:     |.               :|.|...:|        :.::
Zfish   527 KVRRSPLTYGV----GVLNRFVEGKHPPEKMLVKDGMRWCTDVFDTFISADQSVALGETVKRSYT 587

  Fly   453 TASDNQHTVTIQVYEGERP---------MTKDNHLLGKFDLTGI-PPAPRGIPQIEVSF---EID 504
            .|..:|..:.|.||..|:.         :.|...|  |.|::|. .||.|...|..:.|   ||.
Zfish   588 PAKPSQQVIVIHVYCSEKESVTFITDPGVRKCGSL--KLDVSGTESPAARREIQTLMQFGDTEIR 650

  Fly   505 ANGI 508
            |..:
Zfish   651 AMAV 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	111/495 (22%)
		PTZ00009	32..643	CDD:240227	144/641 (22%)
hspa12a	XP_017207164.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900