Protein Alignment Hsc70-3 and Haus8l2

DIOPT Version :10

• Sequence 1: NP_511132.2
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: XP_038944691.1
• Gene: Haus8l2 / 680121
• RGDID: 1595502
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 634
• Identity: 400/634 - (63%)
• Similarity: 499/634 - (78%)
• Gaps: 17/634 - (2%)

  Fly    29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTV 93
            |..:|||||||||||||:::|:||||||||||..|||||||| |.|||||||||||:..||.|||
  Rat     4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNCTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTV 67

  Fly    94 FDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAE 158
            |||||||||.:.|..||.|:|.:||.||....:|.:.|:.....|.|.|||:|:|||.||||.||
  Rat    68 FDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAE 132

  Fly   159 AYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEG-EKNVLV 222
            |||||.||:|||||||||||:|||||||||.||||.|:|||||||||||||.||||.| |:|||:
  Rat   133 AYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYVLDKKVGAERNVLI 197

  Fly   223 FDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQK 287
            |||||||||||:|||::|:|||.:|.|||||||||||.|:::|||..:|:|..|||.::.|||::
  Rat   198 FDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRR 262

  Fly   288 LRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMN 352
            ||...|:|||.||.|.|..|||:|.:||.||..::|||:|||||.||||.||.||:|.|.||.::
  Rat   263 LRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLD 327

  Fly   353 KKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGE--QDTDAIV 415
            |..:|:||||||||||||:|:|::|||.|||.::.|||||||||||||||.:|||:  ::...::
  Rat   328 KSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLL 392

  Fly   416 LLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLG 480
            ||||.||::||||.|||||.||.|||.||||::|.|:|.||||..|.||||||||.|||||:|||
  Rat   393 LLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLG 457

  Fly   481 KFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDA 545
            ||:||||||||||:|||||:|:|||||||.|||.||.||.:.||.||||:.||:.|||:||:::|
  Rat   458 KFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEA 522

  Fly   546 EKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPD 610
            ||:..||:|.:::|.|:|.|||||:::|..:.| :||..|::|::|.|:....:|.|.||::|..
  Rat   523 EKYKAEDEKQRDKVSSKNSLESYAFNMKATVED-EKLQGKINDEDKQKILDKCNEIISWLDKNQT 586

  Fly   611 ADPEEYKKQKKDLEAIVQPVIAKLYQGAGGAP------------PPEGG 647
            |:.||::.|:|:||.:..|:|.||||.|||.|            ||.||
  Rat   587 AEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGG 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_511132.2	PTZ00009	32..643	CDD:240227	395/625 (63%)
Haus8l2	XP_038944691.1	PTZ00009	1..613	CDD:240227	391/610 (64%)