Protein Alignment Hsc70-3 and HSPA13

DIOPT Version :10

• Sequence 1: NP_511132.2
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_008879.3
• Gene: HSPA13 / 6782
• HGNCID: 11375
• Length: 471
• Species: Homo sapiens
• Alignment Length: 423
• Identity: 163/423 - (38%)
• Similarity: 249/423 - (58%)
• Gaps: 52/423 - (12%)

  Fly    31 VIGIDLGTTYSCVGVY--KNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTV 93
            ||||||||||..|||:  ..|:|::|.::.|:...||.|:|| |.:..:|..:.....:||:||:
Human    33 VIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFT-DNDVYVGYESVELADSNPQNTI 96

  Fly    94 FDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAE 158
            :||||.||:.::...::.:|..:||||:.||.....|| ||......:||.:.:.:|.|:||.||
Human    97 YDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSV-TSNETITVSPEYVGSRLLLKLKEMAE 160

  Fly   159 AYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVF 223
            ||||..|.:||::|||.|:..||.:|.:|..:|||:::|:||||||||:||||.|.: ..:|||.
Human   161 AYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHKAD-VFHVLVI 224

  Fly   224 DLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIK-LYKKKKGKDIRKDNRAVQK 287
            ||||||.|||||....|:|...|.:|:..|||:||:||::.:..| :|:.......||:.  :.:
Human   225 DLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEE--IHR 287

  Fly   288 LRREVEKAKRALSGSHQVRIEI---------------------ESFFEGDD-------------- 317
            ||:.||..|..|:.....::.:                     :.....||
Human   288 LRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDK 352

  Fly   318 --------FSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQL 374
                    |...::|..|:.||.|||:..|.|:|:||::..:.|.::.|:||||||||||:::|:
Human   353 KSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQV 417

  Fly   375 VKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSG 407
            :::|| ||:|:..::||.||..|.|:|||:..|
Human   418 IQEFF-GKDPNTSVDPDLAVVTGVAIQAGIDGG 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_511132.2	PTZ00009	32..643	CDD:240227	162/422 (38%)
HSPA13	NP_008879.3	ASKHA_NBD_HSP70_HSPA13	10..452	CDD:466835	163/423 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	315..352		2/36 (6%)