Protein Alignment Hsc70-3 and hspa14

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_001038541.1
• Gene: hspa14 / 565232
• ZFINID: ZDB-GENE-041210-73
• Length: 504
• Species: Danio rerio
• Alignment Length: 521
• Identity: 174/521 - (33%)
• Similarity: 289/521 - (55%)
• Gaps: 53/521 - (10%)

  Fly    32 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA 96
            ||:..|.|.:||.|:|:||.:::|||.|:|:||:.||: .|.|:::|.|||.....|..|||...
Zfish     4 IGVHFGYTCACVAVFKDGRADVVANDAGDRVTPAVVAY-RDTEQIVGIAAKQGRIRNAANTVVKV 67

  Fly    97 KRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYL 161
            |:::||.:.|.:.|...:.....||.|:..|...:||.:..|..:||:::.::..||||||::.|
Zfish    68 KQILGRRYDDPDAQAHKEESKCIVVNKSGLPRYEIDTGETTKYVSPEDVAKLIFHKMKETAQSAL 132

  Fly   162 GKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAY--GLDKKEGEKNVLVFD 224
            |..|..||:|||..|::.|:.|.:.|...||..|:|:|:||:||.:||  |.|...|:.:|||:.
Zfish   133 GSDVKDAVITVPFEFDEMQKNALRQAAESAGFNVLRLIHEPSAALLAYDIGQDSPLGKSHVLVYK 197

  Fly   225 LGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLR 289
            |||.:..|::|.:::||:.|:||..|...|||.|.|.:..|....:||...:|:..:.||:.||.
Zfish   198 LGGTSLSVTVLEVNSGVYRVLATQTDHQTGGESFTQELAQHLAAEFKKTFKQDVSGNARAMMKLM 262

  Fly   290 REVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKK 354
            ...:.||..||........::|.::|.||...::||:||.:...||...::|::.:||..:::..
Zfish   263 NSADVAKHTLSTLGSANCFVDSLYDGMDFECNVSRARFELICSSLFNKCIQPIKSLLEQVNLSTS 327

  Fly   355 DVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDAIVLLD- 418
            ||:::||.|||.||||:||:::|.|...|....|.|||.:..|||:|||:|.|:   |::.|.:
Zfish   328 DVNKVVLSGGSARIPKLQQMIRDLFPDVELLNSIPPDEVIPVGAAMQAGILVGK---DSLALGED 389

  Fly   419 -------VNPLTM------GIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHT---------V 461
                   .:.:|:      |:|    |.|.|.|..|.:|.::          |||         |
Zfish   390 SITVDCCASDITLKEVDDSGLE----VFTVLFPSGTPLPARR----------QHTLQGPGSLSSV 440

  Fly   462 TIQVYEGERPMTKDNHLLGKFDLTGIPPAPR-GIPQIEVSFEIDANGILQVSAEDKGTGNKEKIV 525
            .:|:::.::|:.:  .:||..:       |: .:..:.....:..:|.|.|:..::.:|..|.|.
Zfish   441 RLQLFQAQQPIAQ--IVLGDLE-------PKEELHDVVTVLTMKRDGSLHVTCTEQSSGRSEAIT 496

  Fly   526 I 526
            |
Zfish   497 I 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	143/372 (38%)
		PTZ00009	32..643	CDD:240227	174/521 (33%)
hspa14	NP_001038541.1	HSPA14-like_NBD	2..376	CDD:212680	143/372 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810