Protein Alignment Hsc70-3 and hspa8b

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_001186941.1
• Gene: hspa8b / 562935
• ZFINID: ZDB-GENE-121214-31
• Length: 647
• Species: Danio rerio
• Alignment Length: 624
• Identity: 394/624 - (63%)
• Similarity: 497/624 - (79%)
• Gaps: 7/624 - (1%)

  Fly    29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTV 93
            |..:|||||||||||||:::|:|||||||||||.|||||||| |.|||||||||||:..||.|||
Zfish     4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVALNPTNTV 67

  Fly    94 FDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAE 158
            |||||||||.:.|..||.|:|.:||.|:..|.:|.:.|:.....|.|.|||:|:|||.||||.||
Zfish    68 FDAKRLIGRRFDDAVVQSDMKHWPFTVINDNLRPKVQVEYKGETKTFYPEEVSSMVLTKMKEIAE 132

  Fly   159 AYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEG-EKNVLV 222
            |||||.:|:||:||||||||:|||||||||.|:||.|:||||||||||||||||||.| |:|||:
Zfish   133 AYLGKTITNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNVLI 197

  Fly   223 FDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQK 287
            |||||||||||:|||::|:|||.:|.|||||||||||.|::.|||..:|:|..|||..:.|||::
Zfish   198 FDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVTHFISEFKRKYKKDISDNKRAVRR 262

  Fly   288 LRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMN 352
            ||...|:|||.||.|.|..|||:|.:||.||..::|||:|||||.||||.||.||:|.|.||.::
Zfish   263 LRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKSLRDAKLD 327

  Fly   353 KKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGE--QDTDAIV 415
            |..||:||||||||||||:|:|::|||.|||.::.|||||||||||||||.:|.|:  ::...::
Zfish   328 KSQVHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILCGDKSENVQDLL 392

  Fly   416 LLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLG 480
            ||||.||::||||.|||||.||.|||.||||::|.|:|..|||..|.||||||||.|||||:|||
Zfish   393 LLDVTPLSLGIETAGGVMTILIKRNTTIPTKQTQTFTTYCDNQPGVLIQVYEGERAMTKDNNLLG 457

  Fly   481 KFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDA 545
            ||:||||||||||:|||||:|:||||||:.|||.||.||.:.||.||||:.||:.|||:||:::|
Zfish   458 KFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEA 522

  Fly   546 EKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPD 610
            ||:..||...:|:|.::|.||||::::|:.:.| :||..|:|:::|.|:.:..:|.|.||::|..
Zfish   523 EKYKAEDDVQREKVSAKNGLESYSFNMKSTVED-EKLKGKISEEDKQKIINKCNEVISWLDKNQT 586

  Fly   611 ADPEEYKKQKKDLEAIVQPVIAKLYQGAGGAPP--PEGG 647
            |:.||::.|:|:||.:..|:|.|||||.||.|.  |.||
Zfish   587 AEKEEFEHQQKELEKLCNPIITKLYQGTGGMPEGMPGGG 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	255/374 (68%)
		PTZ00009	32..643	CDD:240227	389/613 (63%)
hspa8b	NP_001186941.1	PTZ00009	1..613	CDD:240227	386/610 (63%)
		HSPA1-2_6-8-like_NBD	6..380	CDD:212675	255/374 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.730