Protein Alignment Hsc70-3 and hspa12a.3

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_001038346.3
• Gene: hspa12a.3 / 559031
• ZFINID: ZDB-GENE-030131-8896
• Length: 571
• Species: Danio rerio
• Alignment Length: 603
• Identity: 128/603 - (21%)
• Similarity: 234/603 - (38%)
• Gaps: 156/603 - (25%)

  Fly    32 IGIDLGTTYSCVGV---YKNGRVEIIANDQGNRI------TPSYVAFTADGERLIGDAAKNQLTT 87
            |.||.||:||...:   .|..:..|...:.|...      ||:.:.|
Zfish     8 IAIDFGTSYSGYAISFKTKQPQESIQIPNWGVNFGYNTFKTPTCILF------------------ 54

  Fly    88 NPENTVF-----DAKRLIGREWSDTNVQHDIKF--FPFKVVEKNSKPHISVDTSQGAKVFAPEEI 145
             .|:..|     ||.....|....:..:....|  |..::.:|.....:.:....|.::.|....
Zfish    55 -DEHETFQKFGYDAMMTYTRSTPKSQARKSFLFEHFKMELYDKEIHRDLMITAKNGGQMKALTVF 118

  Fly   146 SAMV-------LGKMKE--TAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQV----MR 197
            |..:       |.|:||  |.:.::...||. |:||||.:|.|.:|..::|.:.|||.:    .|
Zfish   119 SESLRYLKDHALEKIKENTTGKTFIASDVTW-VLTVPAIWNAAAKQFMREAAIEAGLVIESEPER 182

  Fly   198 II--NEPTAAAI--------AY--------GLDKKEGEKNVLVFDLGGGTFDVSLLTI--DNGVF 242
            ::  .||.||:|        .|        .|::|.|.: .:|.|.||||.|:::..:  |..:.
Zfish   183 LVFALEPEAASIYCKQLPSEGYISEEACRDTLEQKPGTQ-YMVVDCGGGTIDITVHEVVEDGKLK 246

  Fly   243 EVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRA-VQKLRREVEKAKRALSGSHQVR 306
            |:.|.:|: .:||:..|::.:....:::.:|......:|..| ..||:.::..||   |....|.
Zfish   247 ELNAASGN-DMGGQTVDRKFISFLKEIFSEKIYNKFEQDFPAEALKLKYDIALAK---SCDQLVL 307

  Fly   307 IE--------------IESFFEG------DDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADM 351
            |:              |||:|||      |:.|..:...|.:....:..::|.:.::|::.:.::
Zfish   308 IQCPVTLQDLAKKEKAIESYFEGVEGAEWDEGSIIIKEDKLQSFFDESLKTTAEKLEKIMSNPEL 372

  Fly   352 NKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGA---AVQAGVLSGEQDTDA 413
            |   :..::||||......:::.:|:.|...:....:.|...:..||   |.|..|:...
Zfish   373 N---IEYMLLVGGFAECKILKKFLKERFDKCKIVCPVEPQVVIIKGAIRYAKQPKVVKSR----- 429

  Fly   414 IVLLDVNPLTMGIETVGGVMTKLIPR------------------NTVIPTKKS-------QVFST 453
                 ::.||.||. :.....|::.:                  .|.:...:|       |.|..
Zfish   430 -----MSALTYGIR-IDAPFDKVLHKGKTSYVNSEGQTYCDVCFETFVRKGESVNCDEVRQFFFN 488

  Fly   454 ASD-NQHTVTIQVYEGERPMTKDNHL----------LGKFDLTGIPPAPRGIPQIEVSFEIDANG 507
            .|| ||...|.|.:.     |.:..:          :|.|.: |:|....|:.: |:..||....
Zfish   489 PSDTNQTFATFQFFS-----TNEKQVQFIDEPGVESVGVFQV-GMPKTDGGLSR-EIKLEIKFGS 546

  Fly   508 I-LQVSAEDKGTGNKEKI 524
            . ::.:|.|..:|....:
Zfish   547 TEMKATATDVDSGETTSV 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	100/443 (23%)
		PTZ00009	32..643	CDD:240227	128/603 (21%)
hspa12a.3	NP_001038346.3	HSPA12_like_NBD	6..420	CDD:212671	98/439 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900