Protein Alignment Hsc70-3 and Hspa14

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_056580.2
• Gene: Hspa14 / 50497
• MGIID: 1354164
• Length: 509
• Species: Mus musculus
• Alignment Length: 508
• Identity: 175/508 - (34%)
• Similarity: 284/508 - (55%)
• Gaps: 19/508 - (3%)

  Fly    32 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA 96
            ||:.||.|.:||.|||:||.:::|||.|:|:||:.||: ::.|:::|.|||.....:..:||...
Mouse     4 IGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAIVAY-SEREQVVGLAAKQSRIRHVSSTVVKV 67

  Fly    97 KRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYL 161
            |:::||..:|...|..|......|:|||.|....:||.:..|:..||:::.::..||||||.:.|
Mouse    68 KQILGRSSADPQAQKYISESKCLVIEKNGKLRYEIDTGEETKLVNPEDVARLIFSKMKETAHSVL 132

  Fly   162 GKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGL--DKKEGEKNVLVFD 224
            |......|||||..|.:.|:.|..:|...||..|:|:|:||:||.:|||:  |...|:.|||||.
Mouse   133 GSDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDHPTGKSNVLVFK 197

  Fly   225 LGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFD----QRVMDHFIKLYKKKKGKDIRKDNRAV 285
            |||.:..:|::.:::|::.|::||...::||..|.    |.:...|.:|:|    .|:|.:.||:
Mouse   198 LGGTSLSLSVMEVNSGMYRVLSTNTSDNIGGAHFTDTLAQYLASEFQRLFK----HDVRGNARAM 258

  Fly   286 QKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDAD 350
            .||....|.||.:||........::|.:||.||...::||:||.|...||....:.::::|....
Mouse   259 MKLMNSAEVAKHSLSTLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCTEAIRELLRQTG 323

  Fly   351 MNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDT--DA 413
            ....|::::||.|||:||||:|||:||.|...:....|.|||.:..|||::||:|.|::.|  |.
Mouse   324 FTADDINKVVLCGGSSRIPKLQQLIKDLFPAVDLLNSIPPDEVIPIGAAIEAGILVGKESTSGDD 388

  Fly   414 IVLLDVNP---LTMGIETVGG-VMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGE-RPMT 473
            .|:::.:.   |..|::..|. ..|.|.|..|.:|.::..... |.....:|.:::||.| :...
Mouse   389 SVMIECSAKDILVKGVDESGADRFTVLFPSGTPLPARRQHTLQ-APGRVSSVCLELYESEGKNSA 452

  Fly   474 KDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVI 526
            |:.....:..|..:.....|:..|.....:..:|.|||:..|:.||..|.|.:
Mouse   453 KEEAKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQDTGKCEAITV 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	142/376 (38%)
		PTZ00009	32..643	CDD:240227	175/508 (34%)
Hspa14	NP_056580.2	HSPA14-like_NBD	2..376	CDD:212680	142/376 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810