Protein Alignment Hsc70-3 and Hsp70Bb

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Alignment Length: 626
• Identity: 378/626 - (60%)
• Similarity: 480/626 - (76%)
• Gaps: 10/626 - (1%)

  Fly    32 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA 96
            |||||||||||||||::|:|||||||||||.|||||||| |.||||||.||||:..||.||||||
  Fly     4 IGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFT-DSERLIGDPAKNQVAMNPRNTVFDA 67

  Fly    97 KRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYL 161
            ||||||::.|..:..|:|.:|||||....||.|.|:....:|.|||||||:|||.||||||||||
  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132

  Fly   162 GKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKK-EGEKNVLVFDL 225
            |:.:|.||:||||||||:|||||||||.||||.|:||||||||||:||||||. :||:|||:|||
  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197

  Fly   226 GGGTFDVSLLTIDNG-VFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLR 289
            ||||||||:||||.| :|||.:|.|||||||||||.|::.|..:.:|:|..||:|.:.||:::||
  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLR 262

  Fly   290 REVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKK 354
            ...|:|||.||.|.:..|||::.|||.||...::||:||||..||||:||:||:|.|.||.|:|.
  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327

  Fly   355 DVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQD--TDAIVLL 417
            .:|:||||||||||||||.|:::||.||..:..|||||||||||||||.:|||:|.  ...::|:
  Fly   328 QIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392

  Fly   418 DVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKF 482
            ||.||::||||.||||||||.||..||.|:::.|||.||||..|:||||||||.|||||:.||.|
  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTF 457

  Fly   483 DLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEK 547
            ||:||||||||:|||||:|::||||||.|||::..||..:.|.|.||:.||:..:||||:.:|||
  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522

  Fly   548 FADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPDAD 612
            :||||:|.::|:.|||.||||.:::|..:  :.....||.:.:||.:....:|:|:||:.|..|:
  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQSV--EQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAE 585

  Fly   613 PEEYKKQKKDLEAIVQPVIAKLYQ---GAGGAPPPEGGDDA 650
            .||:..:.::|.....|::.|::|   ||.|.|....|..|
  Fly   586 KEEFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQA 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	251/372 (67%)
		PTZ00009	32..643	CDD:240227	375/617 (61%)
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	378/626 (60%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	252/375 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464230
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	P	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.740