Protein Alignment Hsc70-3 and Hsc70-2

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 613
• Identity: 361/613 - (58%)
• Similarity: 473/613 - (77%)
• Gaps: 7/613 - (1%)

  Fly    32 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA 96
            ||||||||||||||::|.:|||||||||||.|||||||. :.||||||.||||:..|.:||||||
  Fly     7 IGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFN-ETERLIGDPAKNQVAMNAKNTVFDA 70

  Fly    97 KRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYL 161
            ||||||::.|..:|.|:|.:||||:.:..||.|.|:.....|.|||||||:|||.||:|.||.||
  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYL 135

  Fly   162 GKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKK-EGEKNVLVFDL 225
            |.||..|||||||||||:|||||||||.||||.|:||||||||||:||||||. :||:|||:|||
  Fly   136 GGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 200

  Fly   226 GGGTFDVSLLTIDNG-VFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLR 289
            ||||||||:|:||.| :|||.||.|||||||||||.|:::||.:.:|:|...||:.:.||:::||
  Fly   201 GGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRLR 265

  Fly   290 REVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKK 354
            ...|:|||.||.|.:..:||::..||.||...::||:|||||:||||||::||::.|.||.|:||
  Fly   266 TACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDKK 330

  Fly   355 DVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLS--GEQDTDAIVLL 417
            .:|::|||||||||||:|:|::|.||||:.:..|||||||||||||||.:|:  |......::|:
  Fly   331 AIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLLV 395

  Fly   418 DVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKF 482
            ||.||::||||.|||||.|:.||..||.|:.|:|:|.||||:.||||||||||.|||||:|||.|
  Fly   396 DVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGTF 460

  Fly   483 DLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEK 547
            :||||||||||:|||||:|:::|:|||.|:|:|..||..|||.|:||:.||:..:||||:.:|||
  Fly   461 NLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEK 525

  Fly   548 FADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPDAD 612
            :..||.:.:|||:|:|.||:|.|:.:..:.|..  ...||:.|::|:.........||::|..|:
  Fly   526 YKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP--SGVLSETERSKVRDKCSSEASWLDKNSLAE 588

  Fly   613 PEEYKKQKKDLEAIVQPVIAKLYQGAGG 640
            .||::...|:.:.|..|:::|::.|..|
  Fly   589 KEEFESHLKECQRICTPIMSKIHGGKKG 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	244/372 (66%)
		PTZ00009	32..643	CDD:240227	361/613 (59%)
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	361/613 (59%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	245/375 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464231
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	P	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.750