Protein Alignment Hsc70-3 and Hsc70-5

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_001286414.1
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Alignment Length: 652
• Identity: 327/652 - (50%)
• Similarity: 432/652 - (66%)
• Gaps: 35/652 - (5%)

  Fly    17 LGEEKKEKDKEL-GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDA 80
            :..:.:.|..|: |.|||||||||.||:.|.:..:.::|.|.:|.|.|||:||||.|||||:|..
  Fly    39 ISSQLRYKSGEVKGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMP 103

  Fly    81 AKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEI 145
            ||.|..||..||.:..||||||.:.|..|:.||....:||| |.|.....|.::.| ||::|.:|
  Fly   104 AKRQAVTNSANTFYATKRLIGRRFDDPEVKKDITNLSYKVV-KASNGDAWVSSTDG-KVYSPSQI 166

  Fly   146 SAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYG 210
            .|.:|.||||||||||...|.:|||||||||||:|||||||||.||||.|:|:||||||||:|||
  Fly   167 GAFILMKMKETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYG 231

  Fly   211 LDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKG 275
            :||.| :|.:.|:||||||||:|:|.|..|||||.:|||||.|||||||..:::..:..:||..|
  Fly   232 MDKTE-DKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSG 295

  Fly   276 KDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGD-----DFSETLTRAKFEELNLDLF 335
            .||||||.|:|:|:...||||..||.|.|..|.: .:...|     ..:..|||:|.|.|..||.
  Fly   296 IDIRKDNIAMQRLKEAAEKAKCELSSSQQTDINL-PYLTMDAAGPQHMNLKLTRSKLESLVGDLI 359

  Fly   336 RSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAV 400
            :.|::|.||.|.||:::|.::.|::||||.||:||||..|::.| |::|||.:|||||||.||||
  Fly   360 KRTIQPCQKALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAV 423

  Fly   401 QAGVLSGEQDTDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQV 465
            |.|||:|  |...::||||.||::||||:|||.|:||.|||.||||||||||||||.|..|.|:|
  Fly   424 QGGVLAG--DVTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKV 486

  Fly   466 YEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQ 530
            ::|||.|..||.|||.|.|.||||||||:|||||.|:||||||:.|||:|||||.:::||| ...
  Fly   487 HQGEREMANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVI-QSS 550

  Fly   531 NRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLE 595
            ..|:.::|:.||:.||::|..||:.:|.:|..|:.||..:..:.::   ::..::|..:|..||:
  Fly   551 GGLSKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKM---EEFKSQLPAEECEKLK 612

  Fly   596 SAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQ--------------GAGGAPPPEG 646
            ..|.:....|.....||.||.:|....|    |....||::              |||.:.....
  Fly   613 KEIADLRTLLANKETADLEEVRKATSSL----QQSSLKLFELAYKKMSAERESNAGAGSSDSSSS 673

  Fly   647 GD 648
            .|
  Fly   674 SD 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	208/378 (55%)
		PTZ00009	32..643	CDD:240227	322/629 (51%)
Hsc70-5	NP_001286414.1	dnaK	51..666	CDD:234715	322/629 (51%)
		HSPA9-like_NBD	51..428	CDD:212683	209/381 (55%)
		Syntaphilin	<566..>642	CDD:291936	21/82 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464218
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D237853at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850