Protein Alignment Hsc70-3 and F11F1.1

DIOPT Version :10

• Sequence 1: NP_511132.2
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_001255199.1
• Gene: F11F1.1 / 3565569
• WormBaseID: WBGene00008714
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 604
• Identity: 237/604 - (39%)
• Similarity: 360/604 - (59%)
• Gaps: 10/604 - (1%)

  Fly    32 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA 96
            ||||||||:|||..|:||:|.|:.|:.|.|.|||.:|...||:.|||..||: :.....|::||.
 Worm     3 IGIDLGTTFSCVAYYQNGQVNILENENGCRTTPSVLAVGEDGDLLIGQHAKD-VIGKATNSLFDV 66

  Fly    97 KRLIGREWSDTNVQHDIKFFPFKVVEK--NSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEA 159
            ||:|||.:.|..:|.|:..:||| |||  |..|::.:..::....|:...:|:::|..:|..||.
 Worm    67 KRIIGRRYDDVLLQRDMPLWPFK-VEKDDNGIPYLEIHKNEKPLKFSAVTVSSLILRCLKYNAER 130

  Fly   160 YLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGL-DKKEGEKNVLVF 223
            .||.:|..||:|||||||..||:||::|..||||:|:||:||||||||||.| .::...:|:|::
 Worm   131 KLGLEVKSAVITVPAYFNATQRRATEEAAEIAGLKVLRILNEPTAAAIAYSLKGQRLSRRNILIY 195

  Fly   224 DLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKL 288
            |||||||||:.:.:|.....|.|..|||||||:|.|..:|...::.:|.:.|.|::.:.||::::
 Worm   196 DLGGGTFDVAAVNVDGPRITVKAKGGDTHLGGQDIDNIIMIKMLEEFKNRHGIDLKGNYRALKRI 260

  Fly   289 RREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNK 353
            |:..|.||..||.|...|||:|....|.||...::|..||....:|..:|:..|::|:.:|::.|
 Worm   261 RKAAEVAKITLSASSVARIELECLHLGIDFIMRISRTDFESWIENLLMATVIHVERVIREANLKK 325

  Fly   354 KDVHEIVLVGGSTRIPKVQQLVKDFF-GGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDAIVLL 417
            ..::||||||||||||.::.::|..| ........|:||||||||||:.|.||||.::...:.|:
 Worm   326 SQINEIVLVGGSTRIPILKNIIKQSFESNTRICESIHPDEAVAYGAAIMAAVLSGAEEVQDMRLI 390

  Fly   418 DVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKF 482
            ||.|:::|::.....|:.||.:.||.|..|.:.|..:.|.|.::.:.||||||.:...|..||:.
 Worm   391 DVIPMSIGVQCNRDYMSVLIKKGTVFPCTKRKTFINSDDFQTSINVPVYEGERVLCSHNRQLGEI 455

  Fly   483 DLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEK 547
            .|. |.|..||...::::.|:|.|||||.:|.|..|.......|..|....|..:||.|...:|:
 Worm   456 SLP-IQPKRRGESVVDITLEVDYNGILQATALDLNTKKAITTTILYDCCTYTQPEIDEMTSQSEE 519

  Fly   548 FADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPDAD 612
            ....|:..|.|.:...:.|..||..|:::   :|:...:...:.:.|...::..|.||...|...
 Worm   520 DRIFDEHFKMRYKQLQKSEDMAYGYKHRL---EKVKGSVEPGKFSNLMETVEREISWLSVFPKVS 581

  Fly   613 PEEYKKQKKDLEAIVQPVI 631
            |.||.::::.|...|.|.:
 Worm   582 PNEYMQRRRALRLKVYPTL 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_511132.2	PTZ00009	32..643	CDD:240227	237/604 (39%)
F11F1.1	NP_001255199.1	ASKHA_NBD_HSP70_HSPA1-like	2..378	CDD:466878	168/376 (45%)