Protein Alignment Hsc70-3 and CG2918

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Alignment Length: 685
• Identity: 187/685 - (27%)
• Similarity: 306/685 - (44%)
• Gaps: 113/685 - (16%)

  Fly     1 MKLCILL-AVVAFVGLSLGEEKKEKDKELGTVIGIDLGTTYSCVGVYKNG-RVEIIANDQGNRIT 63
            |||.:|| |::|.:.||.|          ..|:.:|||:.:..|||...| .:||..|.:..|.|
  Fly     1 MKLVLLLSALLAGIALSQG----------AAVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRKT 55

  Fly    64 PSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVV----EKN 124
            |:.:|| .||.|.||:.|:.....:|.:.......|:|:...:..|....|.||:..:    |:|
  Fly    56 PAILAF-RDGTRTIGEDAQTIGIKDPNSAYGYLLDLLGKTIDNPIVDLYRKRFPYYNIVGDPERN 119

  Fly   125 SKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGV 189
            :......||.:    |:.||:.|.:|.|.|:.|:..:.:.:|..|:|||.||..|:|:|...|..
  Fly   120 TVVFRKSDTDE----FSVEELVAQLLVKAKQFAQESVQQPITECVLTVPGYFGQAEREALLSAAQ 180

  Fly   190 IAGLQVMRIINEPTAAAIAYGLDKKEGEKN-----VLVFDLGGGTFDVSLLTID----------N 239
            :|.|:|:::||:..|.|:.||:..: ||.|     .|.:|:|......::::..          |
  Fly   181 LANLKVLQLINDYAAVALNYGVFHR-GEINETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREIN 244

  Fly   240 GVFEVVATNGDTHLGGEDFDQRVMDHFIKLYK--KKKGKDIRKDNRAVQKLRREVEKAKRALSGS 302
            .|.:|:....|..|||.:...|:.|:..:.:.  ||...|:....||:.||.:|..:.|..||.:
  Fly   245 PVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFNALKKTKTDVTTSPRALAKLFKEAGRLKNVLSAN 309

  Fly   303 HQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTR 367
            .:...:||:..|..||...:||.|.|:|..||:....||:::.|..:.::...:::::|.||.||
  Fly   310 TEFFAQIENLIEDIDFKLPVTREKLEQLCEDLWPRATKPLEEALASSHLSLDVINQVILFGGGTR 374

  Fly   368 IPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDAIVLLDVN--PLTMGIE--- 427
            :|:||:.:|... .:|..:.:|.||:...||..:|..||........|:.|..  ||.:..|
  Fly   375 VPRVQETIKAVI-KQELGKNLNADESATMGAVYKAADLSAGFKVKKFVVKDATLFPLQVSFERDP 438

  Fly   428 ----TVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVY----EGERPMTKDNHLLGKFDL 484
                .|..|...|.......|.||...|     |:||...:.|    :.:|...::...||..::
  Fly   439 GDGAAVKQVKRALFALMNPYPQKKVITF-----NKHTDDFEFYVNYADLDRYSKEEIAALGSLNV 498

  Fly   485 TGIPPAPRGIPQIEVSFE------IDANGI-LQVSAEDKG----TG-----NKEKIVITNDQNRL 533
            |.:.     :.|::...|      :|..|| .....:|.|    ||     .|:|
  Fly   499 TKVQ-----LKQVKELLEKSKKELVDNKGIKAYFYLDDSGIFRCTGVEYVYEKQK---------- 548

  Fly   534 TPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAI 598
             |||          .||||..|       ::..|....|..:.|::.|     .:.|:.:..:|.
  Fly   549 -PED----------DADEDSTL-------SKFGSTLSKLFTKEGEEKK-----DNSEQEEAANAG 590

  Fly   599 DESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAK 633
            :|..| .|.|..|..|:..|::|..|:..|...||
  Fly   591 EEPSK-SEDNEKAKEEDASKEQKSEESTKQDTEAK 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	117/395 (30%)
		PTZ00009	32..643	CDD:240227	176/653 (27%)
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	177/654 (27%)
		HYOU1-like_NBD	23..409	CDD:212672	116/392 (30%)
		TAF4	<572..>627	CDD:296797	16/59 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464229
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740