Protein Alignment Hsc70-3 and Hspa12b

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_001381945.1
• Gene: Hspa12b / 311427
• RGDID: 1312004
• Length: 685
• Species: Rattus norvegicus
• Alignment Length: 708
• Identity: 137/708 - (19%)
• Similarity: 236/708 - (33%)
• Gaps: 263/708 - (37%)

  Fly    19 EEKKEKDKELGTVIGIDLGTTYSCVGVYKNGRVEIIANDQ----------------GNRITPSYV 67
            |.:..:......|:.||.|||.|       |.....|.|.                .::.||:.:
  Rat    50 EVRAPQRASFSVVVAIDFGTTSS-------GYAFSFATDPEAIHMMRKWEGGDPGVAHQKTPTCL 107

  Fly    68 AFTADG-ERLIGDAAKNQL-TTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHIS 130
            ..|.:| ....|..|::.. ..:||.         .|:|        :.|..||:     |.|.:
  Rat   108 LLTPEGIFHSFGYTARDYYHDLDPEE---------ARDW--------LYFEKFKM-----KIHSA 150

  Fly   131 VDTS--------QGAKVFAPEEISAMV-------LGKMKETAEAYLGKKVTHAVVTVPAYFNDAQ 180
            .|.:        .|.|:.|.|..:..:       |.:::|.:|..|.|.....|:||||.:....
  Rat   151 TDLTLKTQLEAVNGKKMLALEVFAHALRFFKEHALQELREQSECMLEKDAVRWVLTVPAIWKQPA 215

  Fly   181 RQATKDAGVIAGL------QVMRIINEPTAAAI-----------------AYG------------ 210
            :|..::|..:|||      :.:.|..||.||::                 |.|
  Rat   216 KQFMREAAYLAGLVSREDAEKLLIALEPEAASVYCRKLRLHQLMDLSSRTAGGGRLGERRSIDSS 280

  Fly   211 ---------------------------LDKKEGEKNVLVFDLGGGTFDVSLLTID--NGVFEVV- 245
                                       .:.:||:: .:|.|.||||.|:::..::  :|..:.:
  Rat   281 FRHAREQLRRSRHSRTFLVESGVGELWSEMQEGDR-YMVADCGGGTVDLTVHQLEQPHGTLKELY 344

  Fly   246 -ATNGDTHLGGED--FDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRRE----------VEKAKR 297
             |:.|.....|.|  |:|.:...|        |:|.      :.|.:|:          ..:|::
  Rat   345 KASGGPYGAVGVDLAFEQLLCRIF--------GEDF------IAKFKRQRPAAWVDLTIAFEARK 395

  Fly   298 ALSGSHQV-RIEIESFFEGDDF------------------------SETLTRAKFEELNLDLFRS 337
            ..:|.|:. .:.|...|...||                        |:.:.|...|.:| :||:.
  Rat   396 RTAGPHRAGALNISLPFSFIDFYRKQRGHNVETALRRSSVNFVKWSSQGMLRMSCEAMN-ELFQP 459

  Fly   338 TLKPVQKVLED--ADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAV 400
            |:..:.:.:|.  |....:.|..:.||||......:|..|::..|    :||:........|..:
  Rat   460 TVSGIIQHIEMLLAKPEVQGVKLLFLVGGFAESAVLQHAVQEALG----NRGLRVVVPHDVGLTI 520

  Fly   401 QAG-VLSGEQDTDAIVLLDVNPLTMGIETVGGVMTKLIP-------------------------- 438
            ..| ||.|:  ...:|.:..:|||.|:    ||:.:.:|
  Rat   521 LKGAVLFGQ--APGVVRVRRSPLTYGV----GVLNRFVPGHHPPEKLLVRDGRRWCTDVFERFVA 579

  Fly   439 --RNTVIPTKKSQVFSTASDNQHTVTIQVY----EGERPMTKDNHLLGKFDLTGIPPAPRGIPQI 497
              ::..:..:..:.:..|...|..|.|.:|    |..|.:|              .|..|....:
  Rat   580 AEQSVALGEEVRRSYCPARPGQRRVLINLYCCAAEDARFIT--------------DPGVRKCGAL 630

  Fly   498 EVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKL 555
              |.|::..|    |.|:.||....                 |.||.|.:|.|.:.|:
  Rat   631 --SLELEPEG----SPENTGTSPSR-----------------REIRAAMQFGDTEIKV 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	100/511 (20%)
		PTZ00009	32..643	CDD:240227	135/695 (19%)
Hspa12b	NP_001381945.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900