Protein Alignment Hsc70-3 and Hspa12a

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: XP_017444569.1
• Gene: Hspa12a / 307997
• RGDID: 1305531
• Length: 691
• Species: Rattus norvegicus
• Alignment Length: 672
• Identity: 156/672 - (23%)
• Similarity: 239/672 - (35%)
• Gaps: 235/672 - (34%)

  Fly    31 VIGIDLGTTYS-----------CVGVYKNGRVEIIANDQG--NRITPSYVAFTADGE-RLIGDAA 81
            |:.||.|||.|           |:.|.:...    ..|.|  |:.||:.:..|.:.: ...|.||
  Rat    74 VVAIDFGTTSSGYAYSFTKEPECIHVMRRWE----GGDPGVSNQKTPTTILLTPERKFHSFGYAA 134

  Fly    82 K---NQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDT----SQGAKV 139
            :   :.|..|      :||:.:..|             .|| ::.::...:::||    :.|.||
  Rat   135 RDFYHDLDPN------EAKQWLYLE-------------KFK-MKLHTTGDLTMDTDLTAANGKKV 179

  Fly   140 FAPEEISAMVLGKMKETAEAYLGKKV--------THAVVTVPAYFNDAQRQATKDAGVIAGL--- 193
            .| .||....|...||.|...|..:.        ...|:||||.:....:|..::|...|||
  Rat   180 KA-LEIFTYALQYFKEQALKELSDQAGSDFENSDVRWVITVPAIWKQPAKQFMREAAYQAGLASP 243

  Fly   194 ---QVMRIINEPTAAAI--------------------AYGL------------------------ 211
               :.:.|..||.||:|                    .|..
  Rat   244 ENSEQLIIALEPEAASIYCRKLRLHQMIELSSKAVVNGYSASDTVGAGFAQAKEHVRRNRQSRTF 308

  Fly   212 -----------DKKEGEKNVLVFDLGGGTFDVSL--LTIDNGVFEVV--ATNGDTHLGGEDFDQR 261
                       :.:||:|.|:| |.||||.|:::  :.:..|..:.:  ||.|.....|.|::
  Rat   309 LVENVIGEIWSELEEGDKYVVV-DSGGGTVDLTVHQIRLPEGHLKELYKATGGPYGSLGVDYE-- 370

  Fly   262 VMDHFIKLYKKKKGKDIRKDNRAVQKLRREV---------EKAKRALSGSHQVRIEIE---SF-- 312
                |.||..|..|:|..:.    .|::|..         |..|||.:......:.|.   ||
  Rat   371 ----FEKLLCKIFGEDFIEQ----FKIKRPAAWVDLMIAFESRKRAAAPDRTNPLNITLPFSFID 427

  Fly   313 ----FEGD-----------DF----SETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHE 358
                |.|.           ||    |:.:.|...:.:|. ||:.|:..:.:.|.|. ..|.:|..
  Rat   428 YYKKFRGHSVEHALRKSNVDFVKWSSQGMLRMSPDAMNA-LFKPTIDSIIEHLRDL-FQKPEVST 490

  Fly   359 I---VLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAG-VLSGEQDTDAIVLLDV 419
            :   .||||....|.:||.|:..||.|  .|.|.|.:.   |..:..| ||.|..  .|::.:..
  Rat   491 VKFLFLVGGFAEAPLLQQAVQAAFGDK--CRIIIPQDV---GLTILKGAVLFGLD--PAVIKVRR 548

  Fly   420 NPLTMGIETVGGVMTKLI-----PRNTVIP-------------------------TKKSQVFSTA 454
            :|||.|:    ||:.:.:     |...::.                         .|:|  ::.|
  Rat   549 SPLTYGV----GVLNRYVEGKHPPEKLLVKDGTRWCTDVFDKFISADQSVALGELVKRS--YTPA 607

  Fly   455 SDNQHTVTIQVYEGER--------PMTKDNHLLGKFDLTGIP----PAPRGIPQIEVSF---EID 504
            ..:|..:.|.:|..|.        |..|....| :.||||..    ||.|.| |..:.|   ||.
  Rat   608 KPSQLVIIINIYSSENDDVSFITDPGVKKCGTL-RLDLTGTSGAAVPARREI-QTLMQFGDTEIK 670

  Fly   505 ANGILQVSAEDKGTGNKEKIVI 526
            |      :|.|..|....|:.|
  Rat   671 A------TAVDIATSKSVKVGI 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	116/501 (23%)
		PTZ00009	32..643	CDD:240227	155/671 (23%)
Hspa12a	XP_017444569.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900