Protein Alignment Hsc70-3 and hsp70.3

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_571472.2
• Gene: hsp70.3 / 30671
• ZFINID: ZDB-GENE-110713-1
• Length: 643
• Species: Danio rerio
• Alignment Length: 631
• Identity: 398/631 - (63%)
• Similarity: 498/631 - (78%)
• Gaps: 15/631 - (2%)

  Fly    29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTV 93
            |..||||||||||||||:::|:|||||||||||.|||||||| |.|||||||||||:..||.|||
Zfish     6 GIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPNNTV 69

  Fly    94 FDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAE 158
            |||||||||.:.|..||.|:|.:.||||....||.::|:.....|.|.|||||:|||.||||.||
Zfish    70 FDAKRLIGRRFDDPVVQSDMKHWSFKVVSDGGKPKVAVEHKGENKTFNPEEISSMVLVKMKEIAE 134

  Fly   159 AYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDK-KEGEKNVLV 222
            ||||:|||:||:||||||||:||||||||||||||.|:||||||||||||||||| |..|:|||:
Zfish   135 AYLGQKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKSSERNVLI 199

  Fly   223 FDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQK 287
            |||||||||||:|||::|:|||.||.|||||||||||.|:::||::.:|:|..|||.::.||:::
Zfish   200 FDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISQNKRALRR 264

  Fly   288 LRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMN 352
            ||...|:|||.||.|.|..|||:|.:||.||..::|||:||||..||||.||.||:|.|.||.|:
Zfish   265 LRTACERAKRTLSSSSQASIEIDSLYEGIDFYTSITRARFEELCSDLFRGTLDPVEKALRDAKMD 329

  Fly   353 KKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGE-----QDTD 412
            |..:|:||||||||||||:|:|::|||.|:|.::.|||||||||||||||.:|.|:     ||
Zfish   330 KAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDTSGNVQD-- 392

  Fly   413 AIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNH 477
             ::||||.||::||||.|||||.||.|||.||||::|.|:|.||||..|.|||:||||.|||||:
Zfish   393 -LLLLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNN 456

  Fly   478 LLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMI 542
            |||||:||||||||||:|||||:|:|||||||.|||.||.||.:.||.||||:.||:.|:|:||:
Zfish   457 LLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKQNKITITNDKGRLSKEEIERMV 521

  Fly   543 RDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQ 607
            ::|:|:..||...:|::.::|.|||||:::||.:.| |.|..|:|:::|.::....:|::.|||.
Zfish   522 QEADKYKAEDDLQREKISAKNSLESYAFNMKNSVED-DNLKGKISEEDKKRVIEKCNEAVSWLEN 585

  Fly   608 NPDADPEEYKKQKKDLEAIVQPVIAKLYQGAGGAPPPEGGDDADLK 653
            |..||.|||:.|.|:||.:..|||:|||||.    .|.||..|..:
Zfish   586 NQLADKEEYEHQLKELEKVCNPVISKLYQGG----MPAGGCGAQAR 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	257/374 (69%)
		PTZ00009	32..643	CDD:240227	393/616 (64%)
hsp70.3	NP_571472.2	PTZ00009	5..643	CDD:240227	398/631 (63%)
		HSPA1-2_6-8-like_NBD	8..383	CDD:212675	257/375 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.730