Protein Alignment Hsc70-3 and T14G8.3

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_001024913.1
• Gene: T14G8.3 / 181422
• WormBaseID: WBGene00011771
• Length: 921
• Species: Caenorhabditis elegans
• Alignment Length: 646
• Identity: 181/646 - (28%)
• Similarity: 304/646 - (47%)
• Gaps: 105/646 - (16%)

  Fly    32 IGIDLGTTYSCVGVYKNG-RVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFD 95
            :.||||:.:..:|:.|.| .::|:.|.:..|.||:.::|..| ||...:||....:::|:::...
 Worm    29 MSIDLGSQFIKIGLVKPGVPMDIVLNKESRRKTPNVISFKND-ERFFAEAAAAMSSSHPQSSYNF 92

  Fly    96 AKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEE-------ISAMVLGKM 153
            ...:|.|:..|.......|.|||...|        .|..:...||..:|       :.||:|...
 Worm    93 LLSMIARKEGDDAFVTFQKTFPFTAFE--------FDEVRKTVVFPYKEEKYNVETLLAMILWNA 149

  Fly   154 KETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKK---- 214
            |:..|||..:.|...|:|||.:.|.|:|:|...|..||||.:::::|:.:|||:.||:.::
 Worm   150 KKVTEAYADQTVKDVVITVPIFLNQAERRAIASAAEIAGLNLLQLLNDGSAAALNYGVFRRKEIT 214

  Fly   215 EGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNG--------------DTHLGGEDFDQRVMDH 265
            |...::|::|:|...   :..||...|.|....:|              |..|||.:...|:.||
 Worm   215 EKPTHMLIYDMGAVK---TTATIVQYVLESTRKDGKDKQPTLRTVGVGFDKTLGGLEITNRLRDH 276

  Fly   266 FIKLYKK--KKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFE 328
            ..|:::.  |..|||..:.||:.||.:|.|:.|:.||.:.....::||.||..:|...:||.:.|
 Worm   277 LEKVFRDTVKTSKDISTNARAIGKLHKEAERVKQVLSANKDTYAQVESLFEEQNFRAKVTREELE 341

  Fly   329 ELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEA 393
            ::..||......|:...:..|.::..|:..:||:|..||:|||::::|.....||.|..:|.|||
 Worm   342 KMIEDLEPRIAAPILDAIGMAQISTNDIDLVVLMGAGTRVPKVKEILKTILKDKEISNFLNTDEA 406

  Fly   394 VAYGAAVQAG-------VLSGEQDTDAIVLLDVNPLTMGIE-TVGGVMTKLIPRNTVIPTKKSQV 450
            :|.||..||.       ||........:..:.||.||...| |:..:...|...|..:|.:...
 Worm   407 IAMGAVYQAAHLSKSFKVLPFNVHEKILYPVFVNFLTKTEEGTMKPIRKSLFGENYPVPNRVMH- 470

  Fly   451 FSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRG--------IPQIEVSFEIDANG 507
            ||:.||: ..:.||        ..|.:.|...:::|:..|...        :..::.:|.||.:|
 Worm   471 FSSYSDD-FKIDIQ--------DADKNPLSTVEISGVKDAIEKEVTDENSVLKGVKTTFSIDLSG 526

  Fly   508 ILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSL 572
            |:.|   :|.:...||:.        |||:.|:...|.::| ||.:|.:|.::.:.:.|.
 Worm   527 IVSV---EKASVVVEKVP--------TPEEKDKYEVDKKEF-DEWEKEQEELKKKEKAEK----- 574

  Fly   573 KNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAK 633
                  |:|       :||.|.|.  :|     |:|.||..||  |.::..|.:.:||:.|
 Worm   575 ------KEK-------EEKKKTEG--EE-----EKNEDAAGEE--KTEEKTEEVEKPVVVK 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	121/398 (30%)
		PTZ00009	32..643	CDD:240227	181/646 (28%)
T14G8.3	NP_001024913.1	HYOU1-like_NBD	29..416	CDD:212672	121/398 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910