Protein Alignment Hsc70-3 and hsp-3

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_001370435.1
• Gene: hsp-3 / 180880
• WormBaseID: WBGene00002007
• Length: 661
• Species: Caenorhabditis elegans
• Alignment Length: 663
• Identity: 508/663 - (76%)
• Similarity: 581/663 - (87%)
• Gaps: 9/663 - (1%)

  Fly     1 MKLCILLAVVAFVGLSL---GEEKKE-KDKELGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNR 61
            ||...||.::|...:|:   .|||.| |:.:.||:||||||||||||||||||||||||||||||
 Worm     1 MKTLFLLGLIALSAVSVYCEEEEKTEKKETKYGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNR 65

  Fly    62 ITPSYVAFTAD-GERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNS 125
            ||||||||:.| |:||||||||||||.|||||:|||||||||:::|..||.|||.:||||::|::
 Worm    66 ITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFDAKRLIGRDYNDKTVQADIKHWPFKVIDKSN 130

  Fly   126 KPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVI 190
            ||.:.|......|.|.|||:|||||.||||.||:||||:|.:|||||||||||||||||||||.|
 Worm   131 KPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTI 195

  Fly   191 AGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG 255
            |||.|:||||||||||||||||||:||:|:|||||||||||||:||||||||||:||||||||||
 Worm   196 AGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGG 260

  Fly   256 EDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSE 320
            ||||||||::||||||||.|||:|||.||||||||||||||||||..||.::||||.|:|:||||
 Worm   261 EDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLRREVEKAKRALSTQHQTKVEIESLFDGEDFSE 325

  Fly   321 TLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPS 385
            |||||||||||:||||:|||||||||||:|:.|.||||||||||||||||||||:|:||.|||||
 Worm   326 TLTRAKFEELNMDLFRATLKPVQKVLEDSDLKKDDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPS 390

  Fly   386 RGINPDEAVAYGAAVQAGVLSGEQDTDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQV 450
            ||||||||||||||||.||:|||:||..||||||||||||||||||||||||.||||||||||||
 Worm   391 RGINPDEAVAYGAAVQGGVISGEEDTGEIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQV 455

  Fly   451 FSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAED 515
            ||||:|||.||||||:|||||||||||.||||||||:||||||:|||||:||||.||||.|:|||
 Worm   456 FSTAADNQPTVTIQVFEGERPMTKDNHQLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAED 520

  Fly   516 KGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKD 580
            ||||||.||.||||||||:||||:|||.||||||::|||:|::.|:|||||||||:|||||.||:
 Worm   521 KGTGNKNKITITNDQNRLSPEDIERMINDAEKFAEDDKKVKDKAEARNELESYAYNLKNQIEDKE 585

  Fly   581 KLGAKLSDDEKNKLESAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQ--GAGGAPP 643
            |||.||.:|:|..:|.|::|:|.||..|.:|..||.|:||||||:.|||:::|||:  ||||...
 Worm   586 KLGGKLDEDDKKTIEEAVEEAISWLGSNAEASAEELKEQKKDLESKVQPIVSKLYKDAGAGGEEA 650

  Fly   644 PEGGDDADLKDEL 656
            ||.|.|.  ||||
 Worm   651 PEEGSDD--KDEL 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	307/374 (82%)
		PTZ00009	32..643	CDD:240227	487/613 (79%)
hsp-3	NP_001370435.1	PTZ00009	32..648	CDD:240227	488/615 (79%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159533
Domainoid	1	1.000	938	1.000	Domainoid score	I10
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3908
Inparanoid	1	1.050	996	1.000	Inparanoid score	I145
Isobase	1	0.950	-	0	Normalized mean entropy	S109
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D237853at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		otm14422
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	LDO	PTHR19375
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R525
SonicParanoid	1	1.000	-	-		X2187
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790