Protein Alignment Hsc70-3 and hsp-6

DIOPT Version :10

• Sequence 1: NP_511132.2
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_001370558.1
• Gene: hsp-6 / 178873
• WormBaseID: WBGene00002010
• Length: 657
• Species: Caenorhabditis elegans
• Alignment Length: 645
• Identity: 328/645 - (50%)
• Similarity: 433/645 - (67%)
• Gaps: 22/645 - (3%)

  Fly    16 SLGEEKKEKDKELGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDA 80
            ||...:...||..|.|||||||||.|||.:.:....::|.|.:|.|.|||.||||||||||:|..
 Worm    18 SLMSARSLSDKPKGHVIGIDLGTTNSCVSIMEGKTPKVIENAEGVRTTPSTVAFTADGERLVGAP 82

  Fly    81 AKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEI 145
            ||.|..||..||:|..||||||.:.|..||.|:|..|:|:| |.|.....|: :|| ||::|.::
 Worm    83 AKRQAVTNSANTLFATKRLIGRRYEDPEVQKDLKVVPYKIV-KASNGDAWVE-AQG-KVYSPSQV 144

  Fly   146 SAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYG 210
            .|.||.|||||||:|||..|.:|||||||||||:|||||||||.|:||.|:|:||||||||:|||
 Worm   145 GAFVLMKMKETAESYLGTTVNNAVVTVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYG 209

  Fly   211 LDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKG 275
            |||..|:|.:.|:||||||||||:|.|..|||||.:|||||.|||||||..::.|.:..:||::|
 Worm   210 LDKDAGDKIIAVYDLGGGTFDVSILEIQKGVFEVKSTNGDTFLGGEDFDHALVHHLVGEFKKEQG 274

  Fly   276 KDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDD-----FSETLTRAKFEELNLDLF 335
            .|:.||.:|:|:||...||||..||.:.|..|.: .:...|.     .:..|||||||::..||.
 Worm   275 VDLTKDPQAMQRLREAAEKAKCELSSTTQTDINL-PYITMDQSGPKHLNLKLTRAKFEQIVGDLI 338

  Fly   336 RSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAV 400
            :.|::|.:|.|.||::....:.:::||||.:|:||||..|::.| ||.||:.:|||||||.|||:
 Worm   339 KRTIEPCRKALHDAEVKSSQIADVLLVGGMSRMPKVQATVQEIF-GKVPSKAVNPDEAVAMGAAI 402

  Fly   401 QAGVLSGEQDTDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQV 465
            |..||:|  |...::||||.||::||||:||:|||||.|||.||||||||||||:|.|..|.|:|
 Worm   403 QGAVLAG--DVTDVLLLDVTPLSLGIETLGGIMTKLITRNTTIPTKKSQVFSTAADGQTQVQIKV 465

  Fly   466 YEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQ 530
            ::|||.|...|.|||:|.|.||||||||:||:||:|:||||||:.|||.|:|||.:::||| ...
 Worm   466 FQGEREMATSNKLLGQFSLVGIPPAPRGVPQVEVTFDIDANGIVNVSARDRGTGKEQQIVI-QSS 529

  Fly   531 NRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLE 595
            ..|:.:.|:.||::|||.|.||.|.||.||..|:.|...:..:.::   .:...:|..||...|.
 Worm   530 GGLSKDQIENMIKEAEKNAAEDAKRKELVEVINQAEGIIHDTEAKM---TEFADQLPKDECEALR 591

  Fly   596 SAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQGA--GGAPPPEGGDDADLK 653
            :.|.::.|.|:...:..||..|:....|    |....||::.|  ..|....|||..:.|
 Worm   592 TKIADTKKILDNKDNETPEAIKEACNTL----QQQSLKLFEAAYKNMAAKNSGGDAQEAK 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_511132.2	PTZ00009	32..643	CDD:240227	318/617 (52%)
hsp-6	NP_001370558.1	dnaK	30..646	CDD:234715	323/630 (51%)