Protein Alignment Hsc70-3 and hsp-1

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_503068.1
• Gene: hsp-1 / 178507
• WormBaseID: WBGene00002005
• Length: 640
• Species: Caenorhabditis elegans
• Alignment Length: 616
• Identity: 399/616 - (64%)
• Similarity: 492/616 - (79%)
• Gaps: 6/616 - (0%)

  Fly    32 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA 96
            :|||||||||||||:.:|:|||||||||||.|||||||| |.|||||||||||:..||.||||||
 Worm     7 VGIDLGTTYSCVGVFMHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPHNTVFDA 70

  Fly    97 KRLIGREWSDTNVQHDIKFFPFKVVE-KNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAY 160
            ||||||::.|..||.|:|.:||||:. :.:||.:.|:.....|:|.|||||:|||.||||||||:
 Worm    71 KRLIGRKFDDPAVQSDMKHWPFKVISAEGAKPKVQVEYKGENKIFTPEEISSMVLLKMKETAEAF 135

  Fly   161 LGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKK-EGEKNVLVFD 224
            ||..|..|||||||||||:|||||||||.||||.|:|||||||||||||||||| .||:|||:||
 Worm   136 LGTTVKDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKKGHGERNVLIFD 200

  Fly   225 LGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLR 289
            |||||||||:|||::|:|||.:|.|||||||||||.|:::||...:|:|..||:..:.||:::||
 Worm   201 LGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFCAEFKRKHKKDLASNPRALRRLR 265

  Fly   290 REVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKK 354
            ...|:|||.||.|.|..|||:|.|||.||...:|||:||||..||||||:.||:|.|.||.|:|.
 Worm   266 TACERAKRTLSSSSQASIEIDSLFEGIDFYTNITRARFEELCADLFRSTMDPVEKSLRDAKMDKS 330

  Fly   355 DVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQD--TDAIVLL 417
            .||:||||||||||||||:|:.|.|.|||.::.|||||||||||||||.:|||::.  ...::||
 Worm   331 QVHDIVLVGGSTRIPKVQKLLSDLFSGKELNKSINPDEAVAYGAAVQAAILSGDKSEAVQDLLLL 395

  Fly   418 DVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKF 482
            ||.||::||||.|||||.||.|||.||||.:|.|:|.||||..|.||||||||.|||||:|||||
 Worm   396 DVAPLSLGIETAGGVMTALIKRNTTIPTKTAQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKF 460

  Fly   483 DLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEK 547
            :|:||||||||:|||||:|:|||||||.|||.||.||.:.||.||||:.||:.:||:||:.:|||
 Worm   461 ELSGIPPAPRGVPQIEVTFDIDANGILNVSATDKSTGKQNKITITNDKGRLSKDDIERMVNEAEK 525

  Fly   548 FADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPDAD 612
            :..:|:..|:|:.::|.|||||::||..|.| :||..|:|.::|.|:|...||.:|||:.|..|:
 Worm   526 YKADDEAQKDRIGAKNGLESYAFNLKQTIED-EKLKDKISPEDKKKIEDKCDEILKWLDSNQTAE 589

  Fly   613 PEEYKKQKKDLEAIVQPVIAKLYQGAGGAPP 643
            .||::.|:||||.:..|:|:||||.||||||
 Worm   590 KEEFEHQQKDLEGLANPIISKLYQSAGGAPP 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	255/372 (69%)
		PTZ00009	32..643	CDD:240227	397/614 (65%)
hsp-1	NP_503068.1	PTZ00009	1..614	CDD:240227	392/608 (64%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	256/375 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.730