Protein Alignment Hsc70-3 and F44E5.4

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_496509.1
• Gene: F44E5.4 / 174805
• WormBaseID: WBGene00009691
• Length: 645
• Species: Caenorhabditis elegans
• Alignment Length: 627
• Identity: 368/627 - (58%)
• Similarity: 476/627 - (75%)
• Gaps: 16/627 - (2%)

  Fly    32 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA 96
            |||||||||||||:|:||:|||:||.:||:.|||||||| |.|||:|||||:|...|||||||||
 Worm     7 IGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFT-DTERLVGDAAKDQAARNPENTVFDA 70

  Fly    97 KRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYL 161
            ||||||.:.::.||.|.|.:||.|..|..||.|.|:.....:.|.|||||||||.|||||||.||
 Worm    71 KRLIGRRFDESTVQSDCKHWPFGVKGKQGKPVIEVEVKGEKRQFNPEEISAMVLQKMKETAETYL 135

  Fly   162 GKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKK-EGEKNVLVFDL 225
            |..|..||:||||||||:||||||||..||||..:||||||||||:||||||. :.|||||:|||
 Worm   136 GHTVKDAVITVPAYFNDSQRQATKDAATIAGLNAIRIINEPTAAALAYGLDKGIQDEKNVLIFDL 200

  Fly   226 GGGTFDVSLLTIDNG-VFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLR 289
            ||||||||:|:|..| :|||.:|.|||||||||||||::.||:..:|:|.||||..:.||:::||
 Worm   201 GGGTFDVSILSIAEGSIFEVKSTAGDTHLGGEDFDQRMLQHFMNEFKRKTGKDISPNPRAIRRLR 265

  Fly   290 REVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKK 354
            ...|:|||.||.|.:..:|::|.|||.|....:|||:||||..||||.||:||:|.|.||.::|.
 Worm   266 TACERAKRTLSSSSEACVEVDSLFEGIDLCTKITRARFEELCADLFRKTLEPVEKALRDAKLDKS 330

  Fly   355 DVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDA--IVLL 417
            .:.|:||||||||:||:|:|:||||.|||.:..||||||||:||||||.||||.:|...  ::|:
 Worm   331 KIDEVVLVGGSTRVPKIQKLLKDFFNGKELNCSINPDEAVAFGAAVQAAVLSGVKDETIKDVLLV 395

  Fly   418 DVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKF 482
            ||.||::||||.|||||.||.|||.||||..:.|:|.:|||..|:||||||||.||:|||.||.|
 Worm   396 DVAPLSLGIETAGGVMTNLIDRNTRIPTKACKTFTTYADNQPGVSIQVYEGERAMTRDNHRLGTF 460

  Fly   483 DLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEK 547
            :|:||||||||:|||||:|:|||||||.||||||.||...:|.|.|::.|||..|||||:.:|::
 Worm   461 ELSGIPPAPRGVPQIEVTFDIDANGILNVSAEDKSTGKSNRITIQNEKGRLTQSDIDRMVHEAKQ 525

  Fly   548 FADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPDAD 612
            |..||.:.:|||::||:||:||:.:|..:   |:..:|||.::.::.:.|:||:::||:.|..|:
 Worm   526 FEKEDGEQRERVQARNQLEAYAFQIKQAL---DEYSSKLSTEDASRAKEAVDETLRWLDSNSLAE 587

  Fly   613 PEEYKKQKKDLEAIVQPVIAKLYQ--------GAGGAPPPEG 646
            .:|.:.:.|:|:::.|.::.|::|        |..|.|...|
 Worm   588 KDEIEAKDKELKSVCQSILTKMHQSGQSSASAGCAGNPGTAG 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	241/372 (65%)
		PTZ00009	32..643	CDD:240227	366/622 (59%)
F44E5.4	NP_496509.1	PTZ00009	1..645	CDD:240227	368/627 (59%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	243/375 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.730