Protein Alignment Hsc70-3 and hsp-70

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_492485.1
• Gene: hsp-70 / 172757
• WormBaseID: WBGene00002026
• Length: 643
• Species: Caenorhabditis elegans
• Alignment Length: 625
• Identity: 361/625 - (57%)
• Similarity: 471/625 - (75%)
• Gaps: 13/625 - (2%)

  Fly    32 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA 96
            |||||||||||||:|:||:|||:||.:||:.|||||||| |.|||:|||||:|...|||||||||
 Worm     7 IGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFT-DTERLVGDAAKDQAARNPENTVFDA 70

  Fly    97 KRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYL 161
            ||||||.:.:..||.|||.:||.|..|..||.:.|:.....:.|..||||||||.||||||||.|
 Worm    71 KRLIGRRFDEETVQSDIKHWPFTVKGKQGKPVVEVEVKGEKREFNAEEISAMVLQKMKETAEAVL 135

  Fly   162 GKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKK-EGEKNVLVFDL 225
            |..|..||:||||||||:||||||||..||||..:||||||||||:||||||. ..|||:|:|||
 Worm   136 GHSVRDAVITVPAYFNDSQRQATKDAATIAGLNAIRIINEPTAAALAYGLDKGITDEKNILIFDL 200

  Fly   226 GGGTFDVSLLTIDNG-VFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLR 289
            ||||||||:|:|..| :|||.:|.|||||||||||.||:.||:..:|:|.||||..:.||:::||
 Worm   201 GGGTFDVSILSIAEGSIFEVKSTAGDTHLGGEDFDSRVLQHFMTEFKRKTGKDISSNPRAIRRLR 265

  Fly   290 REVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKK 354
            ...|:|||.||.|.:..:|::|.|:|.||...:|||:||||..||||.||:||:|.|.||..:|.
 Worm   266 TACERAKRTLSSSTEATVEVDSLFDGTDFYSKITRARFEELCADLFRKTLEPVEKALRDAKTDKG 330

  Fly   355 DVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDA--IVLL 417
            .:.|:|||||||||||:|:|:|:||.||:.:..||||||||:||||||.||||.:|...  ::|:
 Worm   331 RIDEVVLVGGSTRIPKIQKLLKEFFNGKDLNCSINPDEAVAFGAAVQAAVLSGVKDDTIKDVLLV 395

  Fly   418 DVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKF 482
            ||.||:.||||.|||||.||.|||.||.|.|:.|:|.:|||..|:||||||||.||:|||.||.|
 Worm   396 DVVPLSHGIETAGGVMTNLIDRNTRIPAKASKTFTTYADNQPGVSIQVYEGERAMTRDNHRLGTF 460

  Fly   483 DLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEK 547
            :||||||||||:||::|:|:|||||||.|||.||.||...:|.|.|::.||:..|||||:.:|::
 Worm   461 ELTGIPPAPRGVPQVDVTFDIDANGILNVSAADKSTGRSNRITIRNEKGRLSQADIDRMVNEAKQ 525

  Fly   548 FADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPDAD 612
            |..||...::|:.|||:||:||:.:|..:   ::.|:.||.::..:.:.|::::::|:|:|..||
 Worm   526 FEREDAAQRDRISSRNQLEAYAFQVKQAL---EEHGSLLSAEDAKRAKDAVEDTLRWMERNTLAD 587

  Fly   613 PEEYKKQKKDLEAIVQPVIAKLYQ-----GAGGAPPPEGG 647
            .:|.:.:.|:|::|.|.::.|::|     |:|...|..||
 Worm   588 KDEIEAKDKELKSICQDILTKMHQQEAQSGSGCGNPGSGG 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	238/372 (64%)
		PTZ00009	32..643	CDD:240227	358/619 (58%)
hsp-70	NP_492485.1	PTZ00009	1..643	CDD:240227	361/625 (58%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	240/375 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.730