Protein Alignment Hsc70-3 and Hsc70Cb

DIOPT Version :10

• Sequence 1: NP_511132.2
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: XP_061509666.1
• Gene: Hsc70Cb / 1275989
• VectorBaseID: AGAMI1_015163
• Length: 843
• Species: Anopheles gambiae
• Alignment Length: 700
• Identity: 204/700 - (29%)
• Similarity: 334/700 - (47%)
• Gaps: 109/700 - (15%)

  Fly    30 TVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVF 94
            :|||||.|...|.|.|.|.|.:|.||||...|.|||:||| |...|::|.|||||..||..||:.
Mosquito     2 SVIGIDFGNDSSYVAVAKAGGIETIANDYSLRATPSFVAF-AGRNRVLGVAAKNQQVTNMNNTIG 65

  Fly    95 DAKRLIGREWSDTNVQHDIKFFPFKV-VEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAE 158
            :.|.|:||::.|...|.:::..|:.. ..::....|.|:......||:||:|:||:..|:||.|.
Mosquito    66 NFKELLGRKFDDPRAQEELRSLPYHTEALQDGGIGIRVNYLDEEHVFSPEQITAMLFTKLKEDAF 130

  Fly   159 AYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDK------KEGE 217
            ..|..::...|:|||:||.:|||||..||..|:||.|:|::||.||.|::||..|      :|..
Mosquito   131 KELKTQINDCVITVPSYFTNAQRQALLDAANISGLNVLRLMNETTATALSYGFYKQDLPAPEEKP 195

  Fly   218 KNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDN 282
            :||:..|.|..:..||......|..:::|:..|: :||.|||..:..||.|.::.|...|.....
Mosquito   196 RNVIFVDCGHASLQVSACAFHKGNLKMLASCSDS-VGGRDFDLVLATHFNKEFQTKYKIDASSKK 259

  Fly   283 RAVQKLRREVEKAKRALS-GSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVL 346
            ||..:|..||||.|:.:| .|.::.:.||.|....|...::.|::.|||:..||:.....::|:|
Mosquito   260 RAFLRLMAEVEKLKKNMSANSTKLPLNIECFMNEIDVHSSMQRSEMEELSSHLFKRIETTMRKLL 324

  Fly   347 EDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDT 411
            .|:.:..:::|.:.:||||:|||.::.|::..| ||..|..:|.||||:.|||:|..:||.....
Mosquito   325 LDSKLALEEIHSVEIVGGSSRIPAIKHLIEQIF-GKPASTTLNQDEAVSRGAALQCAILSPAVRV 388

  Fly   412 DAIVLLDVNP---LTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMT 473
            ......||..   |....:|.|....|:..:....|..:    ......:..:||:|:.....:.
Mosquito   389 REFSCTDVQAYPVLISWTDTDGPHEMKVFEQYHAAPFCR----LLTVHRKEPMTIKVHYEPNSIP 449

  Fly   474 KDNHLLGKFDLTGIPPAPRGIPQ-IEVSFEIDANGILQVSA----EDK-----------GTGNKE 522
            ..:..:|.:.:.||.|...|..| ::|...|:.|||:.||:    |.|           ..|:::
Mosquito   450 YPDPFIGTYHVKGIKPDANGEAQEVKVKVRINNNGIITVSSATMYERKESEEPSSPTPTSNGDQQ 514

  Fly   523 KIVITNDQNRLTPE-----------------DIDRMIRDAE------------------------ 546
            |   |.|.|:.:|:                 |.:...:|::
Mosquito   515 K---TGDANQSSPQGDESGKVGEPMDIQEGSDDEHPKKDSKPNDSSGEGWTQRVTRWFTSDKKKK 576

  Fly   547 -----------------------KFADEDKKL-------KERVESRNELESYAYSLKNQIGDKDK 581
                                   |:.:|:.|:       |||:::||.||...|.::.:|.:...
Mosquito   577 VTTKQVELTIDSNTHGFVHTELCKYFEEEMKMIANDRQEKERIDARNALEEQVYEIREKIQEDGA 641

  Fly   582 LGAKLSDDEKNKLESAIDESIKWL-EQNPDADPEEYKKQKKDLEAIVQPV 630
            |...:...:.:.:...::|:..|| |:....:...||::.:.:.|.:.||
Mosquito   642 LHDYIDPQDASAICRELEETENWLYEEGESCEKGVYKERLEKMRAKIDPV 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_511132.2	PTZ00009	32..643	CDD:240227	202/697 (29%)
Hsc70Cb	XP_061509666.1	None