Protein Alignment Hsc70-3 and hsp70

DIOPT Version :9

• Sequence 1: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_001106370.1
• Gene: hsp70 / 100037899
• XenbaseID: XB-GENE-485626
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 640
• Identity: 390/640 - (60%)
• Similarity: 503/640 - (78%)
• Gaps: 14/640 - (2%)

  Fly    29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTV 93
            |..:|||||||||||||:::|:|||||||||||.|||||||| |.|||||||||||:..||:|||
 Frog     5 GVAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPQNTV 68

  Fly    94 FDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAE 158
            |||||||||:::|..||.|:|.:||:||..:.||.:.|:.....|.|.|||||:|||.|||||||
 Frog    69 FDAKRLIGRKFNDPVVQSDLKHWPFQVVSDHGKPKVKVEFKGEEKTFFPEEISSMVLIKMKETAE 133

  Fly   159 AYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDK-KEGEKNVLV 222
            ||||..||:||:||||||||:||||||||||||||.|:||||||||||||||||| ..||:|||:
 Frog   134 AYLGHAVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGTRGERNVLI 198

  Fly   223 FDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQK 287
            |||||||||||:||||:|:|||.||.|||||||||||.|:::||::.:|:|..|||.::.||:::
 Frog   199 FDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRMVNHFMEEFKRKHKKDISQNKRALRR 263

  Fly   288 LRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMN 352
            ||...|:|||.||.|.|..|||:|.|||.||..::|||:||||..||||.||:||:|.|.||.::
 Frog   264 LRTACERAKRTLSSSSQASIEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKLD 328

  Fly   353 KKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGE--QDTDAIV 415
            |..:.|||||||||||||||:|::|||.|:|.::.|||||||||||||||.:|.|:  ::...::
 Frog   329 KSQIDEIVLVGGSTRIPKVQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDKSENVQDLL 393

  Fly   416 LLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLG 480
            ||||.||::|:||.|||||.||.|||.||||::|.|:|.||||..|.|||:||||.|||||:|||
 Frog   394 LLDVAPLSLGLETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNNLLG 458

  Fly   481 KFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDA 545
            ||:|:||||||||:|||||:|:|||||||.|||.:|.:|.:.||.||||:.||:.|||::|:::|
 Frog   459 KFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKSSGKQNKITITNDKGRLSKEDIEKMVQEA 523

  Fly   546 EKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPD 610
            |::..:|...:|:::::|.|||||::||:.:.|::..| |:|:.:|..:.....:.|.|||.|..
 Frog   524 ERYKADDDAQREKIDAKNSLESYAFNLKSMVEDENMKG-KISEGDKRIISEKCTQIISWLENNQL 587

  Fly   611 ADPEEYKKQKKDLEAIVQPVIAKLYQG---------AGGAPPPEGGDDADLKDEL 656
            |:.:||..|:|:||.:.||:|.|||||         :.||...:||......:|:
 Frog   588 AEKDEYAFQQKELERVCQPIITKLYQGSMPGSMPGSSCGAQARQGGSSGPTIEEV 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	258/374 (69%)
		PTZ00009	32..643	CDD:240227	386/622 (62%)
hsp70	NP_001106370.1	PTZ00009	2..643	CDD:240227	390/640 (61%)
		HSPA1-2_6-8-like_NBD	7..382	CDD:212675	258/375 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010