DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CkIIbeta and csnk2b

DIOPT Version :9

Sequence 1:	NP_996415.1	Gene:	CkIIbeta / 32132	FlyBaseID:	FBgn0000259	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_571262.1	Gene:	csnk2b / 30428	ZFINID:	ZDB-GENE-990415-29	Length:	215	Species:	Danio rerio

Alignment Length:	215	Identity:	190/215 - (88%)
Similarity:	207/215 - (96%)	Gaps:	0/215 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSSEEVSWVTWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPNYRQALDMILDLEPEDELEDN 65
            |||||||||::|||||||||||||||||||||||||||||||||:|||||||||||||::|||||
Zfish     1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDN 65

  Fly    66 PLQSDMTEQAAEMLYGLIHARYILTNRGIAQMIEKYQTGDFGHCPRVYCESQPMLPLGLSDIPGE 130
            |.|||:.|||||||||||||||||||||||||:||||.||||:|||||||:|||||:||||||||
Zfish    66 PNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGE 130

  Fly   131 AMVKTYCPKCIDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPTNQFVPRLYGFKIHSL 195
            ||||.|||||:||||||||||||||||||||||||||||||||||||||.|||||||||||||.:
Zfish   131 AMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPM 195

  Fly   196 AYQIQLQAAANFKMPLRAQR 215
            |||:|||||::||.|::|.|
Zfish   196 AYQLQLQAASSFKSPVKAIR 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CkIIbeta	NP_996415.1	CK_II_beta	8..191	CDD:198153	166/182 (91%)
csnk2b	NP_571262.1	CK_II_beta	8..191	CDD:198153	166/182 (91%)
csnk2b	NP_571262.1	Interaction with alpha subunit. /evidence=ECO:0000250	188..193		4/4 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580350
Domainoid	1	1.000	374	1.000	Domainoid score	I835
eggNOG	1	0.900	-	-		E1_COG5041
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55572
Inparanoid	1	1.050	416	1.000	Inparanoid score	I1793
OMA	1	1.010	-	-		QHG53662
OrthoDB	1	1.010	-	-		D1335521at2759
OrthoFinder	1	1.000	-	-		FOG0001997
OrthoInspector	1	1.000	-	-		oto41128
orthoMCL	1	0.900	-	-		OOG6_100687
Panther	1	1.100	-	-	LDO	PTHR11740
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R251
SonicParanoid	1	1.000	-	-		X1673
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	1	1.500	-	-
	18	18.300