DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CkIIbeta and Csnk2b

DIOPT Version :9

Sequence 1:	NP_996415.1	Gene:	CkIIbeta / 32132	FlyBaseID:	FBgn0000259	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_001290405.1	Gene:	Csnk2b / 13001	MGIID:	88548	Length:	257	Species:	Mus musculus

Alignment Length:	240	Identity:	135/240 - (56%)
Similarity:	162/240 - (67%)	Gaps:	34/240 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSSEEVSWVTWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPNYRQALDMILDLEPEDELEDN 65
            |||||||||::|||||||||||||||||||||||||||||||||:|||||||||||||::|||||
Mouse     1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDN 65

  Fly    66 PLQSDMTEQAAEMLYGLIHARYILTNRGIAQMIEKYQTGDFGHCPRVYCESQPMLPLGLSDIPGE 130
            |.|||:.|||||||||||||||||||||||||:||||.||||:|||||||:|||||:|   |||
Mouse    66 PNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIG---IPG- 126

  Fly   131 AMVKTYCPKCIDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPTNQFVPRLYGFKIHSL 195
              :::.|      .:|:..||...  .:..|..|.:...||.:.....|..:.:.| :.|..|:|
Mouse   127 --LQSGC------LSPRPFRHPRR--GHGETLLPQVHGRVHTQVLQTPPHGRRILR-HWFPSHAL 180

  Fly   196 --AYQIQLQAAAN--------FK---------MPLRAQRGQPPKD 221
              |.::..||...        |:         .|.|.|..:|.:|
Mouse   181 HGASRVPAQATCQPVCTQALWFQDPSNGLPAAAPSRQQLQEPSQD 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CkIIbeta	NP_996415.1	CK_II_beta	8..191	CDD:198153	116/182 (64%)
Csnk2b	NP_001290405.1	CK_II_beta	8..>129	CDD:198153	106/126 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836839
Domainoid	1	1.000	374	1.000	Domainoid score	I880
eggNOG	1	0.900	-	-		E1_COG5041
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55572
Inparanoid	1	1.050	416	1.000	Inparanoid score	I1801
Isobase	1	0.950	-	0.772836	Normalized mean entropy	S292
OMA	1	1.010	-	-		QHG53662
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001997
OrthoInspector	1	1.000	-	-		oto94205
orthoMCL	1	0.900	-	-		OOG6_100687
Panther	1	1.100	-	-	LDO	PTHR11740
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R251
SonicParanoid	1	1.000	-	-		X1673
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740