DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Karl and PTGDS

DIOPT Version :9

Sequence 1:NP_001285137.1 Gene:Karl / 32131 FlyBaseID:FBgn0030334 Length:266 Species:Drosophila melanogaster
Sequence 2:NP_000945.3 Gene:PTGDS / 5730 HGNCID:9592 Length:190 Species:Homo sapiens


Alignment Length:173 Identity:34/173 - (19%)
Similarity:63/173 - (36%) Gaps:44/173 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 KVGAIKNFDLERMMGCWHVVQYYASTEELPEYACMRSHFSFSKE------DQHITMNFSYIFAED 113
            :|....||..::.:|.|......:::..|.|   .::..|..|.      |..:.:..::     
Human    27 QVSVQPNFQQDKFLGRWFSAGLASNSSWLRE---KKAALSMCKSVVAPATDGGLNLTSTF----- 83

  Fly   114 PLREKLVGNITWMIP--------KFQEPGHWQHTEDIYEGIYNTYVLDTDYDTWGLVMHCAEKKK 170
             ||:......|.::.        .::.| ||..|       |:..|::||||.:.|:.....|..
Human    84 -LRKNQCETRTMLLQPAGSLGSYSYRSP-HWGST-------YSVSVVETDYDQYALLYSQGSKGP 139

  Fly   171 QPRYLSALLLSR----KTSLADNEISFLRGK---------LPQ 200
            ...:..|.|.||    :..|.:...:|.:.:         |||
Human   140 GEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFLPQ 182

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KarlNP_001285137.1 None
PTGDSNP_000945.3 Lipocalin 40..184 CDD:306552 31/160 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D558802at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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