DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Karl and APOD

DIOPT Version :9

Sequence 1:	NP_001285137.1	Gene:	Karl / 32131	FlyBaseID:	FBgn0030334	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	NP_001638.1	Gene:	APOD / 347	HGNCID:	612	Length:	189	Species:	Homo sapiens

Alignment Length:	218	Identity:	43/218 - (19%)
Similarity:	84/218 - (38%)	Gaps:	47/218 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VLIIILDVLLAPVGANLWTRHNSNAYQTRRRSGPSNRCPKVGAIKNFDLERMMGCWHVVQYYAST 80
            :|:::|..|     |.|:......|:..       .:||.....:|||:.:.:|.|:.::...:|
Human     3 MLLLLLSAL-----AGLFGAAEGQAFHL-------GKCPNPPVQENFDVNKYLGRWYEIEKIPTT 55

  Fly    81 EELPEYACMRSHFSFSKEDQHITMNFSYIFAEDPLRE--------------KLVGNITWMIPKFQ 131
            .|  ...|:::::|..:..:...:| ..:.|:..:.:              ||....:|.:|
Human    56 FE--NGRCIQANYSLMENGKIKVLN-QELRADGTVNQIEGEATPVNLTEPAKLEVKFSWFMP--- 114

  Fly   132 EPGHWQHTEDIYEGIYNTYVLDTDYDTWGLVMHCAEKKKQPRYLSALLLSRKTSLADNEISFLRG 196
            ...:|              :|.|||:.:.||..|....:......|.:|:|..:|....:..|:.
Human   115 SAPYW--------------ILATDYENYALVYSCTCIIQLFHVDFAWILARNPNLPPETVDSLKN 165

  Fly   197 KL-PQDIDTSFMFNIGQESCDNL 218
            .| ..:||...|....|.:|..|
Human   166 ILTSNNIDVKKMTVTDQVNCPKL 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Karl	NP_001285137.1	None
APOD	NP_001638.1	lipocalin_apoD-like	25..182	CDD:381212	34/183 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1631943at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10612
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020