DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dy and cutl-4

DIOPT Version :9

Sequence 1:	NP_511130.2	Gene:	dy / 32130	FlyBaseID:	FBgn0004511	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_507484.3	Gene:	cutl-4 / 189246	WormBaseID:	WBGene00012304	Length:	469	Species:	Caenorhabditis elegans

Alignment Length:	535	Identity:	111/535 - (20%)
Similarity:	192/535 - (35%)	Gaps:	162/535 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 QQVQVPDLSVGGSSNNEIWAAPVQDMPKIVSLDVKCEKNGMKVFVQFDKPFNGIVFSKGHYSNMN 284
            |..:||.:..|           :...|:::     |:...:::.::..:.|.|.::|||.:....
Worm    17 QSAKVPRIQNG-----------IVGEPEVI-----CDIKQIRITMRTSQSFIGNLYSKGFFHKSE 65

  Fly   285 CVHLPSGLGRSSA-SFDIGL---HECGTAGNTDNYGQGYGHEAGSTGAGTYFENIIVIQYDPQVQ 345
            |    ...|.|:| |.:|.|   .:||..           .:......|...:.|:::.:.|...
Worm    66 C----RVRGNSTANSIEIVLPVDSDCGIR-----------RKRMMNPRGILLDTIVILMFHPVFL 115

  Fly   346 EVWDQARKLRCTWHDQYEKSVTFRPFPVDMLDV--------------VRADFAGDNVGCWMQI-- 394
            ...|::..::|.:.:. |::||      :.|||              :..|.|   ..|..::
Worm   116 TQTDRSYHVQCQYTES-ERTVT------NALDVSMQPASELPQSIQQLNDDSA---PVCKYEVLM 170

  Fly   395 QVGKGPWASEVSGLVKIGQTMTMVLAIKDDDSK--FDMLVRNCVAHDGKRAPIQLVDQRGCVTRP 457
            :..:||..|..:    :|..:....:. |.::|  :.|.|.:||..||:....:|||:.||....
Worm   171 ENAQGPPLSHAT----VGDLVYHKWSC-DGNNKEMYCMTVHSCVVDDGQGFGQKLVDEHGCTLDA 230

  Fly   458 KLMSRF---TKIKNFGASASVLSYAHFQAFKFPDSMEVHFQCTIQI-----CRYHC---PEQC-- 509
            .::...   .|....|..:||        |||.|...|.|.|.|::     ....|   .|.|
Worm   231 FILKELEYNEKELEAGQMSSV--------FKFADKPTVFFSCMIRVEMKESAEMPCVIPTEVCKN 287

  Fly   510 ---SAETNLQDVHHLQVGPESQYG-PPPQ----LHVDAYHVASAIGKRRD----------ERRVQ 556
               |...||..:...:|..:...| |.||    |.........|:....|          |..|.
Worm   288 LPSSKMQNLDVMTDRKVSDDIPPGFPRPQNNTKLQKSQKFSTDAMTSNSDYSADFLDDELEDEVD 352

  Fly   557 RRARAVAEPQVGLNRIIKVVSSGDLTFAIDDQAGGN----------GSSTNGANSGVDRSPQTMV 611
            :.:|.   |.|.:||:|:           .|.||||          ..|.|     |...|::.|
Worm   353 KMSRI---PSVTMNRLIR-----------RDVAGGNTKLLADVDVAAPSVN-----VQDLPESEV 398

  Fly   612 ----------FPLREEGLICMTTPGFAITLIVL--LGILVTSCLTSAVLYVRL-RPFSSFAGSAK 663
                      .|......:|.|.....::|::|  |||     :|.:::|:.: |...:.:.|.|
Worm   399 GNPTGNRKFHVPTNASNDVCFTRTNLILSLLILAALGI-----VTISLMYLVISRVTENESASRK 458

  Fly   664 ERAVAFTNPQLAPLP 678
            .:.:        |||
Worm   459 TKKL--------PLP 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dy	NP_511130.2	ZP	254..513	CDD:214579	62/296 (21%)
dy	NP_511130.2	Zona_pellucida	<403..510	CDD:278526	30/124 (24%)
cutl-4	NP_507484.3	ZP	35..278	CDD:214579	58/285 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I3981
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960