Protein Alignment dy and dpy-1

DIOPT Version :10

• Sequence 1: NP_511130.2
• Gene: dy / 32130
• FlyBaseID: FBgn0004511
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_001370799.1
• Gene: dpy-1 / 175342
• WormBaseID: WBGene00001063
• Length: 1427
• Species: Caenorhabditis elegans
• Alignment Length: 537
• Identity: 109/537 - (20%)
• Similarity: 182/537 - (33%)
• Gaps: 175/537 - (32%)

  Fly   225 PDLSVGGSSNNEIWAAPVQDM-------PKIV---------------SLDVKCEKNGMKVFVQFD 267
            |..||....|::|....:.|:       |:::               .:|::|..:|.||.|...
 Worm   999 PKYSVKNPENSKILTPVLPDLNENLAESPEVLVTTRPENAETAENSGIIDLECVGDGFKVQVNPP 1063

  Fly   268 KPFNGIVFSKGHYSNMNCVHLPSGLGRSSASFDIGL----HECGTAGNTDNYGQGYGHEAGSTGA 328
            ..|.|:...||:..:..|      ...:|:|..:.|    :|||..           ....|...
 Worm  1064 AGFRGVAVVKGYQDDARC------KATASSSLPLNLFISNNECGVT-----------QVKSSDPN 1111

  Fly   329 GTYFENIIVIQYDPQVQEVWDQARKLRCTWHDQYEKSVTFRPFPVDMLDVVRADFA-GDNVG--- 389
            |.....::.:.:|.::....|:|..|:|....|.:.:|.     ...|:|||::.| .:.:.
 Worm  1112 GLNSSLVLHLLHDDELNTAEDRAYLLQCFIGAQNQDAVV-----STNLNVVRSELAIAETISLST 1171

  Fly   390 ----CWMQIQVGKGPWASEVSGLVKIGQTM--------TMVLAIKDDDSKFDMLVRNCVAHDGKR 442
                |...|: .:||....||..| :|||:        |     .|.:..:.:.|.:|.|.|...
 Worm  1172 LPPTCTYSIR-KEGPEGPIVSRAV-VGQTVWHRWECDGT-----NDTNQAYGIQVHSCYASDDVE 1229

  Fly   443 APIQLVDQRGCVTRPKLMSRFTKIKNFGASASVLSYAHFQAFKFPDSMEVHFQCTIQICRYHCPE 507
            .....||.|||.:...|::..|.     |..|:.::|....|...|:..:.|.|.:.:|. ...:
 Worm  1230 RKFAFVDPRGCSSDLALLTDLTY-----ADDSLTAWAASHVFNVHDAESLKFVCKLSLCT-RDGD 1288

  Fly   508 QCSAETNLQDVHHLQVGPESQYGPPPQLHVDAYHVASAIGKRRDERRVQRRARAVAEPQVGL--- 569
            .|...|                  ||           |.|...               :.||
 Worm  1289 GCEGVT------------------PP-----------ACGNTN---------------KTGLLLT 1309

  Fly   570 NRIIKVVSSGD--LTFAIDDQAGGNGSSTNGANSGVDRSPQTMVFPLREEGLICMTTPGF----- 627
            .|:.|.::|.|  ||.|:..    |...|:|::.|:             |.|:...|..:
 Worm  1310 KRLAKGINSVDEALTSALST----NVKLTSGSSDGL-------------EDLLKSATSSYLFWVV 1357

  Fly   628 ---AITLIVLLGIL----------VTSCLTSAVLYVRLRPFSSFAGSAKERAVAFTNPQLAPLPV 679
               |:..||.:.||          .|:|.....    :.....|.||.:    :.::|   |.|.
 Worm  1358 ALVAVAAIVAISILSRNMAENSDTATTCSDPTT----MSESQDFGGSIR----SISSP---PPPN 1411

  Fly   680 IQLPSPADLQGTLSKKR 696
            .||   ||...:..:.|
 Worm  1412 RQL---ADFMRSFDRNR 1425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dy	NP_511130.2	ZP	254..513	CDD:214579	62/278 (22%)
dpy-1	NP_001370799.1	PAT1	<19..>153	CDD:401645
		VWA	823..975	CDD:459670
		ZP	1050..1299	CDD:214579	66/312 (21%)