Protein Alignment CG9360 and DHRS11

DIOPT Version :10

• Sequence 1: NP_572746.1
• Gene: CG9360 / 32128
• FlyBaseID: FBgn0030332
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: NP_077284.2
• Gene: DHRS11 / 79154
• HGNCID: 28639
• Length: 260
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 105/257 - (40%)
• Similarity: 162/257 - (63%)
• Gaps: 18/257 - (7%)

  Fly     1 MDRWLNRVAVVTGASSGIGAACCKDLVSKGLVVVGLARREDRLQELKASLPADQASRFHGR---- 61
            |:||.:|:|:|||||.|||||..:.||.:||.|||.||....::||.|..   :::.:.|.
Human     6 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAEC---KSAGYPGTLIPY 67

  Fly    62 KCDVSQEQEVIDAFAWIDATLGGADVLVNNAGIVRLGVGITHEGNGADLRAILDTNVLGVSWCTR 126
            :||:|.|::::..|:.|.:...|.|:.:||||:.|....::  |:.:..:.:.:.|||.:|.|||
Human    68 RCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLS--GSTSGWKDMFNVNVLALSICTR 130

  Fly   127 EAFKSLKRRNVNDGHILIVNSVAGHRVINNPGITMGMYSPSKYAVTALTEVLRQEFHNNKTQTKI 191
            ||::|:|.|||:||||:.:||::||||:  |......||.:|||||||||.||||....:|..:.
Human   131 EAYQSMKERNVDDGHIININSMSGHRVL--PLSVTHFYSATKYAVTALTEGLRQELREAQTHIRA 193

  Fly   192 TSISPGAVDTE----IIDKE---ALVGIPDFPMLRSEDVADAISYCIQTPPNVQIHELTIKP 246
            |.||||.|:|:    :.||:   |.........|:.||||:|:.|.:.||.::||.::.::|
Human   194 TCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGDIQMRP 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9360	NP_572746.1	Rossmann-fold NAD(P)(+)-binding proteins	1..246	CDD:473865	104/255 (41%)
DHRS11	NP_077284.2	Mgc4172-like_SDR_c	6..256	CDD:187601	105/257 (41%)