Protein Alignment CG15221 and SV2B

DIOPT Version :9

• Sequence 1: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001309960.1
• Gene: SV2B / 9899
• HGNCID: 16874
• Length: 683
• Species: Homo sapiens
• Alignment Length: 625
• Identity: 128/625 - (20%)
• Similarity: 233/625 - (37%)
• Gaps: 147/625 - (23%)

  Fly     9 DCDREFANMEGGREENL------------SEKPRPHTFEEAITLTGVGRFHYKLLLICGLCFMGV 61
            |...:.|.|...|.::|            .|:...|.:|..:...|.|||.:.|..:.||..|..
Human    58 DVKAKQAKMAPSRMDSLRGQTDLMAERLEDEEQLAHQYETIMDECGHGRFQWILFFVLGLALMAD 122

  Fly    62 MVEIMGVSLIMNQMKCDLQPTLNQQGILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSV 126
            .||:..||..:...:.|:..:.:::|:|....:||::..:..:|.|||..||...|..:|.:::.
Human   123 GVEVFVVSFALPSAEKDMCLSSSKKGMLGMIVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNAS 187

  Fly   127 CSIVSAFSVNIWMLIVFRFLTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPA 191
            .:.:|:|.......:..|.::|..|.|....||:...||.....|..|::.|..|.....::|.|
Human   188 FASLSSFVQGYGAFLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASA 252

  Fly   192 MAIGILPLRIETIVLG--MHFSSWRVLLLANVSIPLLALVGISALPETPKYLLVQGRGDESLEVL 254
            ||..|:|.......:|  .||.||||.::.......:::|.:..:||:|::||..|:.||:..:|
Human   253 MAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDEAWMIL 317

  Fly   255 RSIFANN---SGRDPSEYPVKEVALESGGVSLSDVHG------------FLDAVRLVWHQTVPLF 304
            :.:...|   .|.....:.|..:..........::..            |....:.||...:...
Human   318 KQVHDTNMRAKGTPEKVFTVSNIKTPKQMDEFIEIQSSTGTWYQRWLVRFKTIFKQVWDNALYCV 382

  Fly   305 YRARLWHTLNICCIQFIIYFLAQGIFMWFPTIL----DE-----LGTRNGENTLLCTV------- 353
            ......:||.:..:.|.:.|...|:.:|||.::    ||     :....||:....|:
Human   383 MGPYRMNTLILAVVWFAMAFSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVYGATINFTMENQ 447

  Fly   354 --LQGFNIN--------------------------SSSEDEASSCSVE----VDTSTYQVMII-- 384
              ..|..:|                          :|::....:|::|    .:|..|:...|
Human   448 IHQHGKLVNDKFTRMYFKHVLFEDTFFDECYFEDVTSTDTYFKNCTIESTIFYNTDLYEHKFINC 512

  Fly   385 --IAACFV----------------VIYL--------------IFAYIIDYMGKKNLLMAWMVLTM 417
              |.:.|:                :|||              |.|.::|.:|:..::...|:::.
Human   513 RFINSTFLEQKEGCHMDLEQDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISA 577

  Fly   418 ICLVALHYVEQFALVVIALTVVMAIGN------------CG------GLVSTIAMEFYPTHINAM 464
            :|...|.:                 ||            ||      ..:..|.:|.|||:..|.
Human   578 VCCFFLFF-----------------GNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRAT 625

  Fly   465 GMCFIMMVGRLGAVVGSNILGRLL-FASCDPIFWALLALV 503
            ....:..:.:.||::|:.|....: .....||..|..:||
Human   626 AFGILNGLCKFGAILGNTIFASFVGITKVVPILLAAASLV 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	115/568 (20%)
		MFS	51..488	CDD:119392	110/553 (20%)
SV2B	NP_001309960.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42
		Sugar_tr	8..683	CDD:331684	128/625 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208328at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920