Protein Alignment CG15221 and SLC22A13

DIOPT Version :9

• Sequence 1: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_004247.2
• Gene: SLC22A13 / 9390
• HGNCID: 8494
• Length: 551
• Species: Homo sapiens
• Alignment Length: 466
• Identity: 100/466 - (21%)
• Similarity: 177/466 - (37%)
• Gaps: 94/466 - (20%)

  Fly    96 GVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWMLIVFRFLTGFFISGGQACVFS 160
            |:::.:...|.|.|..||..|:...|.:.::..:.:||..:..:.:..||.....::|......:
Human   147 GLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLATAFVPSFELYMALRFAVATAVAGLSFSNVT 211

  Fly   161 LCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIETIVLGMHFSSWRVLLLANVSIPL 225
            |..|:.|...|.:.|.|......:..:....:|.|              |.:||:|.:...:..|
Human   212 LLTEWVGPSWRTQAVVLAQCNFSLGQMVLAGLAYG--------------FRNWRLLQITGTAPGL 262

  Fly   226 LALVGISALPETPKYLLVQGRGDESLEVLRSIFANNSGRDPSEYPVKEVALESGGVSLSDVHGFL 290
            |......||||:.::||.:||.||::::::.. |:.:.|..|...:.::..|..|.|
Human   263 LLFFYFWALPESARWLLTRGRMDEAIQLIQKA-ASVNRRKLSPELMNQLVPEKTGPS-------- 318

  Fly   291 DAVRLVWHQTVPLFYRARLWH-TLNICCIQFIIYFLAQGIFMWFPTILDELGTRNGENTLLCTVL 354
                   ...:.||...:|.. ||.|.|:             ||   :|.||            .
Human   319 -------GNALDLFRHPQLRKVTLIIFCV-------------WF---VDSLG------------Y 348

  Fly   355 QGFNINSSSEDEASSCSVEVDTSTYQVMIIIAACFVVIYLIFAYIIDYMGKKNLLMAWMVL-TMI 418
            .|.::      :.....::|    |...:|..|..|.......:::...|:|...:..:|| .::
Human   349 YGLSL------QVGDFGLDV----YLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLM 403

  Fly   419 CLVALHYVEQFALVVIALTVV--MAIGNCGGLVSTIAMEFYPTHINAMGMCFIMMVGRLGAVVGS 481
            |::.:.......:||..|.||  ||......:....:.|.:||.:...||..:.:..|:|.::..
Human   404 CIIIIFIPADLPVVVTMLAVVGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTP 468

  Fly   482 NI--LGRLLFASCDPIFWALLALVVLLCTLGYFLPE-----------------KARSQQKKPSAT 527
            .:  ||....|....|:.:|..:..|||||   |||                 ..||.:..||..
Human   469 LVILLGEYHAALPMLIYGSLPIVAGLLCTL---LPETHGQGLKDTLQDLELGPHPRSPKSVPSEK 530

  Fly   528 AKAIVTATTSP 538
            .......|:||
Human   531 ETEAKGRTSSP 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	82/397 (21%)
		MFS	51..488	CDD:119392	82/397 (21%)
SLC22A13	NP_004247.2	2A0119	12..510	CDD:273328	93/433 (21%)
		MFS	139..500	CDD:119392	90/423 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..551		7/31 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153332
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840