Protein Alignment CG15221 and SLC22A14

DIOPT Version :9

• Sequence 1: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_006713479.2
• Gene: SLC22A14 / 9389
• HGNCID: 8495
• Length: 675
• Species: Homo sapiens
• Alignment Length: 483
• Identity: 98/483 - (20%)
• Similarity: 183/483 - (37%)
• Gaps: 128/483 - (26%)

  Fly    71 IMNQ--MKCDLQPTLNQQGILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAF 133
            ::|:  :.|.::...:...|:..|   |:.:.|.....:.|..||...:..:|....:....:||
Human   250 LINEFDLVCGMETKKDTAQIMFMA---GLPIGSLIFRLITDKMGRYPAILLSLLGLIIFGFGTAF 311

  Fly   134 SVNIWMLIVFRF-----LTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMA 193
            ..:..:.:.|||     :.|:.||........|.||...      |..:|..  |.       .|
Human   312 MNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRA------HAIILGH--CF-------FA 361

  Fly   194 IGILPLRIETIVLGMHFS--SWRVLLLAN--VSIPLLALVGISALPETPKYLLVQGRGDESLEVL 254
            :|.:      ::.|:.:|  .|::|.|..  :.||.::.:.|  |||:|::|:::|:..|:.:||
Human   362 VGAV------LLTGIAYSLPHWQLLFLVGGILVIPFISYIWI--LPESPRWLMMKGKVKEAKQVL 418

  Fly   255 RSIFANNSGRDPSEYPVKEVALESGGVSLSDVHGF-----LDAVRLVWHQTVPLFYRARLWHTLN 314
            ....:.|....||.. :.|:.|....|:.:.|..|     |..|.||         .:.:|.|::
Human   419 CYAASVNKKTIPSNL-LDELQLPRKKVTRASVLDFCKNRQLCKVTLV---------MSCVWFTVS 473

  Fly   315 ICCIQFIIYFLAQGIFMWF----PTI------------LDELGTRNGENTLLCTVLQGFNINSSS 363
            .......:.....|:.:.|    |:|            |.::|.:   .:|..|:||.
Human   474 YTYFTLSLRMRELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRK---WSLAVTLLQA------- 528

  Fly   364 EDEASSCSVEVDTSTYQVMIIIAACFVVIYLIFAYIIDYMGKKNLLMAW------MVLTMICLVA 422
                                 |..|.::::|       ..|:..|.:.|      .:.:|..||.
Human   529 ---------------------IIWCLLLLFL-------PEGEDGLRLKWPRCPATELKSMTILVL 565

  Fly   423 LHYVEQFALVVIALTVVMAIGNCGGLVSTIAMEFYPTHINAMGMCFIMMVGRLGAVVGSNILGRL 487
            :  :.:|:|   |.||.:..        ....|..||.:.|.|:..:.:....||::...|:.:.
Human   566 M--LREFSL---AATVTVFF--------LYTAELLPTVLRATGLGLVSLASVAGAILSLTIISQT 617

  Fly   488 LFASCDPIFWALLALVVLLCTLGYFLPE 515
              .|..|||...: |.::..:|...|||
Human   618 --PSLLPIFLCCV-LAIVAFSLSSLLPE 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	89/454 (20%)
		MFS	51..488	CDD:119392	89/454 (20%)
SLC22A14	XP_006713479.2	2A0119	141..650	CDD:273328	98/483 (20%)
		MFS	270..641	CDD:119392	92/460 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153428
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840