Protein Alignment CG15221 and SLC22A6

DIOPT Version :9

• Sequence 1: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_004781.2
• Gene: SLC22A6 / 9356
• HGNCID: 10970
• Length: 563
• Species: Homo sapiens
• Alignment Length: 466
• Identity: 110/466 - (23%)
• Similarity: 172/466 - (36%)
• Gaps: 111/466 - (23%)

  Fly    95 LGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWMLIVFRFLTGFFISG------ 153
            :||:|.:...|:|||..||...|......::|....:||:.|..:...||.|:|..::|
Human   143 VGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCM 207

  Fly   154 ----------GQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIETIVLGM 208
                      .:|||          |:.|.:|..|..||...:.:|       :|
Human   208 TLNVEWMPIHTRACV----------GTLIGYVYSLGQFLLAGVAYA-------VP---------- 245

  Fly   209 HFSSWRVLLLANVSIPLLALVGIS-ALPETPKYLLVQGRGDESLEVLRSIFANNSGRDPSEYPVK 272
               .||.|.|. ||.|..|....| ...|:.::....||.|.:|..|:.:...|..|:.......
Human   246 ---HWRHLQLL-VSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSM 306

  Fly   273 EVALESGGVSLSDVHGFLDAVRLVWHQTVPLFYRARLWHTLNICCIQFIIYFLAQGIFMWFPTIL 337
            ||...|....|:...|...|:.|:         |......|.:|.           ..:||.|..
Human   307 EVLRASLQKELTMGKGQASAMELL---------RCPTLRHLFLCL-----------SMLWFATSF 351

  Fly   338 DELGTRNGENTLLCTVLQGFNINSSSEDEASSCSVEVDTSTYQVMIIIAACFVVIYLIFAYIIDY 402
            ...|        |...||||.:                 |.|.:.:|..|..:...|:...:|:.
Human   352 AYYG--------LVMDLQGFGV-----------------SIYLIQVIFGAVDLPAKLVGFLVINS 391

  Fly   403 MGKKNLLMAWMVLTMICLVALHYVEQFALVVIALTVVMAIG------NCGGLVSTIAMEFYPTHI 461
            :|::...||.::|..||::....:.|...:|.....|:..|      ||   :.....|.|||.|
Human   392 LGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNC---IFLYTGELYPTMI 453

  Fly   462 NAMGMCFIMMVGRLGAVVGSNI-LGRLLFASCDPIF------WALLALVVLLC-TLGYFLPEKAR 518
            ...||.....:.|:|::|...: :...|:.|. |:|      .|..|:.|||. |||..||:..:
Human   454 RQTGMGMGSTMARVGSIVSPLVSMTAELYPSM-PLFIYGAVPVAASAVTVLLPETLGQPLPDTVQ 517

  Fly   519 SQQKKPSATAK 529
            ..:.:.:.|.|
Human   518 DLESRWAPTQK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	94/416 (23%)
		MFS	51..488	CDD:119392	94/416 (23%)
SLC22A6	NP_004781.2	2A0119	11..515	CDD:273328	108/451 (24%)
		MFS	135..505	CDD:119392	102/441 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	525..563		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153410
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840